中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
16期
14-15
,共2页
心血管%高同型半胱氨酸血症%不稳定型心绞痛
心血管%高同型半胱氨痠血癥%不穩定型心絞痛
심혈관%고동형반광안산혈증%불은정형심교통
Cardiovascular%Hyperhomocysteinemia%Unstable angina pectoris
目的:探讨老年患者高同型半胱氨酸血症与不稳定型心绞痛(UAP)的关系,为不稳定型心绞痛的病情观察提供依据。方法:选取2013年1月-2014年12月笔者所在医院收治的老年心绞痛患者100例,其中44例不稳定型心绞痛患者作为UAP组,56例稳定性型心绞痛患者作为SAP组,检测血清同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)及血脂水平。结果:UAP组患者的血清Hcy、TC、TG、LDL和hs-CRP均明显高于SAP组患者,HDL水平明显低于SAP组患者,差异均有统计学意义(P<0.05)。结论:血清Hcy水平与冠状动脉粥样斑块的稳定性密切相关,是UAP发病的危险因素,有效控制老年血清Hcy水平对于UAP的防治具有重要的临床意义。
目的:探討老年患者高同型半胱氨痠血癥與不穩定型心絞痛(UAP)的關繫,為不穩定型心絞痛的病情觀察提供依據。方法:選取2013年1月-2014年12月筆者所在醫院收治的老年心絞痛患者100例,其中44例不穩定型心絞痛患者作為UAP組,56例穩定性型心絞痛患者作為SAP組,檢測血清同型半胱氨痠(Hcy)、超敏C反應蛋白(hs-CRP)及血脂水平。結果:UAP組患者的血清Hcy、TC、TG、LDL和hs-CRP均明顯高于SAP組患者,HDL水平明顯低于SAP組患者,差異均有統計學意義(P<0.05)。結論:血清Hcy水平與冠狀動脈粥樣斑塊的穩定性密切相關,是UAP髮病的危險因素,有效控製老年血清Hcy水平對于UAP的防治具有重要的臨床意義。
목적:탐토노년환자고동형반광안산혈증여불은정형심교통(UAP)적관계,위불은정형심교통적병정관찰제공의거。방법:선취2013년1월-2014년12월필자소재의원수치적노년심교통환자100례,기중44례불은정형심교통환자작위UAP조,56례은정성형심교통환자작위SAP조,검측혈청동형반광안산(Hcy)、초민C반응단백(hs-CRP)급혈지수평。결과:UAP조환자적혈청Hcy、TC、TG、LDL화hs-CRP균명현고우SAP조환자,HDL수평명현저우SAP조환자,차이균유통계학의의(P<0.05)。결론:혈청Hcy수평여관상동맥죽양반괴적은정성밀절상관,시UAP발병적위험인소,유효공제노년혈청Hcy수평대우UAP적방치구유중요적림상의의。
Objective:To investigate the relationship of the hyperhomocysteinemia and unstable angina pectoris(UAP) elderly patients,providing the basis for the observation of unstable angina pectoris disease.Method:100 elderly patients with angina pectoris from January 2013 to December 2014 in our hospital were selected,including 44 cases of unstable angina pectoris patients as UAP group,56 patients with stable angina as SAP group,detection of serum homocysteine(Hcy),high sensitive C reactive protein(hs-CRP) and blood lipid level.Result:The levels of serum Hcy,TC,TG,LDL and hs-CRP of UAP group were significantly higher than those of SAP group,the level of HDL was significantly lower than that of SAP group,there were statistically significant differences(P<0.05).Conclusion:The level of serum Hcy and plaque stability of coronary atherosclerosis are closely related,are the risk factors of UAP, effectively control the elderly the level of serum Hcy has important clinical significance for the prevention and treatment UAP.