CAJ | 학술논문

目的：探究妇科手术术后低分子量肝素干预时间对下肢静脉血栓形成的影响。方法回顾性分析220例行经腹或经阴手术治疗患者的临床资料。根据患者术后低分子量肝素用药时间的不同将其分为A、B、C、D四组，分别为术后12、24、36、48 h给予低分子量肝素治疗，均于脐旁注射5000 IU的低分子肝素。观察各组患者术后的凝血功能情况以及下肢静脉血栓形成的发生率情况。结果 A、B两组患者的DV T发生率明显高于D组，组间比较差异显著且具有统计学意义；C组患者DV T发生率稍高于A、B两组，但稍低于D组患者，组间比较差异不显著，不具有统计学意义。结论低分子量肝素术后干预时机的不同对血栓形成的影响差别较大，术后24 h可作为低分子量肝素预防DV T形成的最佳时机。
목적：탐구부과수술술후저분자량간소간예시간대하지정맥혈전형성적영향。방법회고성분석220례행경복혹경음수술치료환자적림상자료。근거환자술후저분자량간소용약시간적불동장기분위A、B、C、D사조，분별위술후12、24、36、48 h급여저분자량간소치료，균우제방주사5000 IU적저분자간소。관찰각조환자술후적응혈공능정황이급하지정맥혈전형성적발생솔정황。결과 A、B량조환자적DV T발생솔명현고우D조，조간비교차이현저차구유통계학의의；C조환자DV T발생솔초고우A、B량조，단초저우D조환자，조간비교차이불현저，불구유통계학의의。결론저분자량간소술후간예시궤적불동대혈전형성적영향차별교대，술후24 h가작위저분자량간소예방DV T형성적최가시궤。
Objective To explore the effect of low molecular weight heparin intervention time on venous thrombosis after gy‐necological operation .Methods 220 clinical data of patients with gynecological abdominal or vaginal surgery were retrospective analyzed .According to low molecular weight heparin treatment time of patients after gynecological operation ,A ,B ,C ,D four groups were divided ,which were given low molecular weight heparin respectively after 12 ,24 ,36 ,48 h ,were injected 5000 IU of low molecular weight heparin in parumbilical .The blood coagulation function and relatively deep vein thrombosis incidence of patients in each group were observed .Results The deep vein thrombosis (DVT) occurrences of group A ,B were significantly higher than group D ,the difference between groups was statistically significant .The DVT occurrence of group C was slightly higher than group A ,B ,but was slightly lower than group D ,the difference between the two groups was not statistically signifi‐cant .Conclusion The effect of low molecular weight heparin intervention time in the treatment on postoperative thrombosis was different .The 24 h postoperative could be the optimal timing in preventing thrombosis ,when low molecular weight heparin w as used .