CAJ | 학술논문

目的：探讨扩散加权成像(DWI)和表观扩散系数(ADC)值在鉴别儿童小脑常见肿瘤中的价值。方法回顾性分析本院经手术病理证实的45例儿童小脑肿瘤患者,其中髓母细胞瘤23例,星形细胞瘤14例,室管膜瘤8例。测量不同肿瘤的实质部分的最小 ADC 值,绘制 ROC 曲线,预测儿童常见小脑肿瘤鉴别诊断的最佳 ADC 值。结果髓母细胞瘤的平均最小 ADC 值最低,为(0.497±0.023)×10-3 mm2/s；低级星形细胞瘤的平均最小 ADC 值最高,为(1.572±0.145)×10-3 mm2/s；室管膜瘤的平均最小ADC 值为(0.784±0.037)×10-3 mm2/s。髓母细胞瘤鉴别室管膜瘤的最佳 ADC 值为0.611×10-3 mm2/s,敏感度100%,特异性95.7%；室管膜瘤鉴别低级星形细胞瘤的最佳 ADC 值为1.064×10-3 mm2/s,敏感度92.9%,特异性100%。结论ADC 值有助于儿童小脑常见肿瘤的鉴别诊断。
목적：탐토확산가권성상(DWI)화표관확산계수(ADC)치재감별인동소뇌상견종류중적개치。방법회고성분석본원경수술병리증실적45례인동소뇌종류환자,기중수모세포류23례,성형세포류14례,실관막류8례。측량불동종류적실질부분적최소 ADC 치,회제 ROC 곡선,예측인동상견소뇌종류감별진단적최가 ADC 치。결과수모세포류적평균최소 ADC 치최저,위(0.497±0.023)×10-3 mm2/s；저급성형세포류적평균최소 ADC 치최고,위(1.572±0.145)×10-3 mm2/s；실관막류적평균최소ADC 치위(0.784±0.037)×10-3 mm2/s。수모세포류감별실관막류적최가 ADC 치위0.611×10-3 mm2/s,민감도100%,특이성95.7%；실관막류감별저급성형세포류적최가 ADC 치위1.064×10-3 mm2/s,민감도92.9%,특이성100%。결론ADC 치유조우인동소뇌상견종류적감별진단。
Objective To investigate the assessment value of diffusion-weighted magnetic resonance imaging (DWI)and apparent diffusion coefficient (ADC)in the differential diagnosis of common cerebellar tumors of children.Methods 45 patients with cerebel-lar tumors were retrospectively analyzed,including 23 medulloblastomas,14 astrocytomas,and 8 ependymomas .The ADCmin of parenchyma of different tumors were measured and Receiver operating characteristic (ROC)curve were delineated.The optimum ADC value for differential diagnosis of common cerebellar tumors of children was analyzed and determined.Results The mean ADC-min of medulloblastoma (0.497 ± 0.023 )× 10 -3 mm2/s was lowest,the mean ADCmin of astrocytoma (1.572 ± 0.145 )× 10 -3 mm2/s was highest,while that of ependymoma was (0.784 ± 0.037 )× 10 -3 mm2/s.The optimum ADC to distinguish ependymomas from medulloblastomas was 0.61 1 × 10 -3 mm2/s (100% sensitivity and 95.7% specificity).The optimum ADC to distinguish low-grade astrocytomas from ependymomas was 1.064×10 -3 mm2/s (92.9% sensitivity and 100% specificity).Conclu-sion ADC is very helpful with differential diagnosis of common cerebellar tumors of children.