CAJ | 학술논문

目的：评价双源 CT 对痛风性关节炎的诊断价值。方法检索 PubMed、Embase、Cochrane 和万方数据库2014-05前公开发表的所有中英文文献。根据纳入与排除标准筛选出可用的文献。使用双变量随机效应模型和分层综合受试者工作特征曲线(HSROC)模型汇总数据,使用回归分析和敏感性分析探索潜在的异质性来源。结果共纳入文献9篇,汇总敏感度、特异度及其95%可信区间分别为92%(84%~96%)和88%(83%~92%),HSROC 曲线下面积为0.91(0.88~0.93)；结果间有显著的异质性(I 2=85%)。结论采用双源 CT 诊断痛风性关节炎的准确性较高,结果间存在来源不明的异质性。
목적：평개쌍원 CT 대통풍성관절염적진단개치。방법검색 PubMed、Embase、Cochrane 화만방수거고2014-05전공개발표적소유중영문문헌。근거납입여배제표준사선출가용적문헌。사용쌍변량수궤효응모형화분층종합수시자공작특정곡선(HSROC)모형회총수거,사용회귀분석화민감성분석탐색잠재적이질성래원。결과공납입문헌9편,회총민감도、특이도급기95%가신구간분별위92%(84%~96%)화88%(83%~92%),HSROC 곡선하면적위0.91(0.88~0.93)；결과간유현저적이질성(I 2=85%)。결론채용쌍원 CT 진단통풍성관절염적준학성교고,결과간존재래원불명적이질성。
Objective To estimate the diagnostic value of dual-energy CT in gouty arthritis.Methods English and Chinese litera-tures publicated before May 2014 were searched in PubMed,Embase,Cochrane and Wanfang database.Available literatures were selected according to the inclusion and exclusion criterias.Sensitivity,specificity with 95% confidence interval (95% CI)was pooled with bivariate random-effects model.Hierarchical weighted symmetric summary receiver-operating curve (HSROC)was also used in estimating.Meta-regression and sensitivity analysis were used to explore the potential sources of heterogeneity.Results Nine studies were included in the analysis.The pooled sensitivity,specificity and 95% CI were 92%(84-96%)and 88%(83-92%)respectively, area under the HSROC curve was 0.91 (0.88-0.93).There was substantial heterogeneity between studies(I 2 =85%).Conclusion Dual-energy CT is accuracy in diagnosing gouty arthritis.The sources of heterogeneity was not been explored.