CAJ | 학술논문

目的：探讨单骨型纤维结构不良(FD)肉瘤变的临床及影像特征。方法收集经手术病理证实的单骨型 FD 肉瘤变12例,影像检查行 X 线平片12例,CT 7例,MR 5例。结果12例单骨型 FD 肉瘤变中,手术史病例组中(6例),影像显示手术区呈溶骨性骨质破坏,病灶边界不清伴有骨皮质破坏及软组织肿块。6例无手术史病例组 X 线及 CT 显示毛玻璃背景下出现溶骨性骨质破坏区,MRI 显示病灶肿块信号不均质且伴有明显强化。12例患者中,FD 骨肉瘤变9例,纤维肉瘤变2例,恶性纤维组织细胞瘤变1例。结论FD 肉瘤变影像学特征可以为 FD 提供恶变征象。
목적：탐토단골형섬유결구불량(FD)육류변적림상급영상특정。방법수집경수술병리증실적단골형 FD 육류변12례,영상검사행 X 선평편12례,CT 7례,MR 5례。결과12례단골형 FD 육류변중,수술사병례조중(6례),영상현시수술구정용골성골질파배,병조변계불청반유골피질파배급연조직종괴。6례무수술사병례조 X 선급 CT 현시모파리배경하출현용골성골질파배구,MRI 현시병조종괴신호불균질차반유명현강화。12례환자중,FD 골육류변9례,섬유육류변2례,악성섬유조직세포류변1례。결론FD 육류변영상학특정가이위 FD 제공악변정상。
Objective To investigate clinical and imaging features of malignant transformation in monostotic fibrous dysplasia (FD).Methods Radiography (n=12),computed tomography (CT)(n=7)and magnetic resonance imaging (MRI)(n=5)data of 12 monostotic FD cases proved by surgery and pathology were retrospectively reviewed.Results Among 12 cases,6 cases underwent surgery.Their images showed osteolytic lesions in the operative area with direct signs of aggressiveness (poorly defined margin,cor-tical destruction and soft tissue mass).For the 6 cases without surgery,radiography and CT showed poorly margin,osteolytic le-sions within or near the area of ground-glass opacity.MRI showed lesions with heterogeneous signal intensity and pronounced con-trast-enhancement.Histopathologically,9 cases were osteosarcomas,2 cases were fibrosarcomas,and 1 case was malignant fibrous histiocytoma (MFH).Conclusion The imaging information of malignant transformation of FD can provide evidence of possible ma-lignancy.