CAJ | 학술논문

目的：研究卡贝缩宫素不同给药速度对剖宫产术中不良反应发生率的影响。方法收集2012年10月至2013年6月成都市妇女儿童中心医院行剖宫产术的120例产妇临床资料，根据胎儿娩出后卡贝缩宫素100 ug静脉微量泵入速度不同分为两组，60例3 min泵入者纳入高速组，60例6 min泵入者纳入低速组。比较两组产妇术中子宫收缩的评价、产妇术中恶心、呕吐、面部潮红、胸闷和头晕等不良反应发生率的情况。结果两组产妇术中子宫收缩的评价情况、呕吐、胸闷、头晕发生率比较差异无统计学意义（P＞0.05），高速组产妇术中恶心、面部潮红[16.67％（10／60）、20％（12／60）]不良反应发生率高于低速组[5％（3／60）、6.67％（4／60）]（P＜0.05）。结论在不影响子宫收缩的前提下，较低速度的卡贝缩宫素静脉注入方式能够有效降低产妇术中不良反应的发生率。
목적：연구잡패축궁소불동급약속도대부궁산술중불량반응발생솔적영향。방법수집2012년10월지2013년6월성도시부녀인동중심의원행부궁산술적120례산부림상자료，근거태인면출후잡패축궁소100 ug정맥미량빙입속도불동분위량조，60례3 min빙입자납입고속조，60례6 min빙입자납입저속조。비교량조산부술중자궁수축적평개、산부술중악심、구토、면부조홍、흉민화두훈등불량반응발생솔적정황。결과량조산부술중자궁수축적평개정황、구토、흉민、두훈발생솔비교차이무통계학의의（P＞0.05），고속조산부술중악심、면부조홍[16.67％（10／60）、20％（12／60）]불량반응발생솔고우저속조[5％（3／60）、6.67％（4／60）]（P＜0.05）。결론재불영향자궁수축적전제하，교저속도적잡패축궁소정맥주입방식능구유효강저산부술중불량반응적발생솔。
Objective To investigate different injection speed of carbetocin on adverse reactions during cesarean section. Methods Clinical data of 120 pregnant women underwent caesarean section in Chengdu Women’ s and Children’ s Central Hospital from Oct 2012 to Jun 2013 were selected.All cases were divided into two groups according to different injection speed of carbetocin, 60 cases injected within 3 min were selected into high speed group, another 60 cases injected within 6 min were selected into low speed group, The differences in uterine contraction assessment and adverse reactions such as nausea, vomiting, facial flushing, bosom frowsty, dizziness between two groups were compared.Results There was no significant difference in uterine contraction assessment, incidence of vomiting, bosom frowsty, dizziness between two groups ( P>0.05) .The incidence of nausea and facial flushing in high speed group[16.67 %(10/60)、20 % (12/60)]were higher than that in low speed group[5 %(3/60)、6.67 %(4/60)] (P<0.05).Conclusion Under the premise of without affecting uterine contractions, the low speed carbetocin injection can effectively decrease the incidence of adverse reactions during cesarean section.