蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2015年
6期
802-804
,共3页
肺肿瘤%癌胚抗原%糖类抗原125%诊断
肺腫瘤%癌胚抗原%糖類抗原125%診斷
폐종류%암배항원%당류항원125%진단
lung neoplasms%carcinoembryonic antigen%carbohydrate antigen 125%diagnosis
目的：：探讨癌胚抗原(CEA)和糖类抗原125(CA125)检测对肺癌的临床诊断价值。方法：选取2012年6月至2014年5月收治的肺癌患者50例作为肺癌组，同期收治的肺部良性疾病50例作为良性病变组，同期健康体检者50名作为健康对照组，采用电化学发光法检测3组对象血清中CEA和CA125水平，对检测结果进行对比。结果：肺癌组CEA和CA125水平均明显高于良性病变组和健康对照组(P<0.01)，而良性病变组和健康对照组 CEA和 CA125水平差异均无统计学意义(P>0.05)；CEA和CA125联合检测对肺癌诊断的阳性结果与CEA和CA125单独检测差异均无统计学意义(P>0.05)。结论：肺癌患者的CEA和CA125水平会明显升高，检测CEA和CA125能够为肺癌的早期诊断和治疗提供依据。
目的：：探討癌胚抗原(CEA)和糖類抗原125(CA125)檢測對肺癌的臨床診斷價值。方法：選取2012年6月至2014年5月收治的肺癌患者50例作為肺癌組，同期收治的肺部良性疾病50例作為良性病變組，同期健康體檢者50名作為健康對照組，採用電化學髮光法檢測3組對象血清中CEA和CA125水平，對檢測結果進行對比。結果：肺癌組CEA和CA125水平均明顯高于良性病變組和健康對照組(P<0.01)，而良性病變組和健康對照組 CEA和 CA125水平差異均無統計學意義(P>0.05)；CEA和CA125聯閤檢測對肺癌診斷的暘性結果與CEA和CA125單獨檢測差異均無統計學意義(P>0.05)。結論：肺癌患者的CEA和CA125水平會明顯升高，檢測CEA和CA125能夠為肺癌的早期診斷和治療提供依據。
목적：：탐토암배항원(CEA)화당류항원125(CA125)검측대폐암적림상진단개치。방법：선취2012년6월지2014년5월수치적폐암환자50례작위폐암조，동기수치적폐부량성질병50례작위량성병변조，동기건강체검자50명작위건강대조조，채용전화학발광법검측3조대상혈청중CEA화CA125수평，대검측결과진행대비。결과：폐암조CEA화CA125수평균명현고우량성병변조화건강대조조(P<0.01)，이량성병변조화건강대조조 CEA화 CA125수평차이균무통계학의의(P>0.05)；CEA화CA125연합검측대폐암진단적양성결과여CEA화CA125단독검측차이균무통계학의의(P>0.05)。결론：폐암환자적CEA화CA125수평회명현승고，검측CEA화CA125능구위폐암적조기진단화치료제공의거。
Objective:To explore the clinical value of the levels of carcinoembryonic antigen(CEA) and carbohydrate antigen 125 (CA125) in the diagnosis of lung cancer. Methods:Fifty patients with lung cancer and 50 patients with benign lesion from June 2012 to May 2014 were divided into the lung cancer group and benign lesion group, respectively. Fifty healthy people were set as healthy control group. The serum levels of CEA and CA125 in 3 groups were detected using electrochemiluminescence,which was analyzed. Results:The levels of CEA and CA125 in lung cancer group were significantly higher than those in the benign lesion group and healthy control group(P<0. 01),the differences of the levels of CEA and CA125 between the benign lesion group and healthy control group were not statistically significant(P>0. 05). The differences of the positive diagnosis rate between the combined detection of CEA and CA125 and the single CEA or CA125 detection were not statistical significance(P>0. 05). Conclusions:The levels of CEA and CA125 in patients with lung cancer increase significantly. The detection of CEA and CA125 can provide the basis for early diagnosis and treatment of lung cancer.
