CAJ | 학술논문

目的：评价 MR 扩散加权成像(DWI)对实性孤立性肺结节(SPN)的鉴别诊断价值。方法经手术、活检或临床治疗随访后证实的42例 SPN 患者,其中恶性25例,良性17例,全部行 MR 胸部常规 T1 WI、T2 WI 和 DWI 检查,b 值选择300,500,800 s/mm2和1000 s/mm2。分别测量不同 b 值时的表观扩散系数(ADC)值和信号强度。结果良、恶性 SPN 的 ADC 值和信号强度均随 b 值增加而呈逐渐下降趋势。良、恶性 SPN 在 b 值=500 s/mm2时,其 ADC 值有统计学意义(P 500=0.03<0.05)；而 b值在300~1000 s/mm2时,其信号强度值均有统计学意义(P 300<0.001,P 500=0.03<0.05,P 800=0.01<0.05,P 1000=0.02<0.05)。结论DWI 的信号强度和 ADC 值对良、恶性 SPN 鉴别诊断均具有重要临床意义,信号强度值的诊断效能优于 ADC 值。
목적：평개 MR 확산가권성상(DWI)대실성고립성폐결절(SPN)적감별진단개치。방법경수술、활검혹림상치료수방후증실적42례 SPN 환자,기중악성25례,량성17례,전부행 MR 흉부상규 T1 WI、T2 WI 화 DWI 검사,b 치선택300,500,800 s/mm2화1000 s/mm2。분별측량불동 b 치시적표관확산계수(ADC)치화신호강도。결과량、악성 SPN 적 ADC 치화신호강도균수 b 치증가이정축점하강추세。량、악성 SPN 재 b 치=500 s/mm2시,기 ADC 치유통계학의의(P 500=0.03<0.05)；이 b치재300~1000 s/mm2시,기신호강도치균유통계학의의(P 300<0.001,P 500=0.03<0.05,P 800=0.01<0.05,P 1000=0.02<0.05)。결론DWI 적신호강도화 ADC 치대량、악성 SPN 감별진단균구유중요림상의의,신호강도치적진단효능우우 ADC 치。
Objective To evaluate the value of diffusion weighted imaging (DWI)in distinguishing the solid solitary pulmonary nodule (SPN).Methods 42 patients with SPN (malignant in 25 and benign in 1 7)who were confirmed by operation,biopsy or follow up after treatment underwent routine chest T1 WI,T2 WI and DWI.The b values were chosen as 300,500,800 and 1 000 s/mm2 ,and the corresponding apparent diffusion coefficient (ADC)values and the signal intensity (SI)were respectively measured.Results The ADC values and SI of benign and malignant SPNs were gradually reduced with increasing b value.The ADC value between benign and malignant SPNs was statistically significant with b value of 500 s/mm2 (P 500 =0.03 <0.05 ),meanwhile the SI was statistically significant with b values from 300 to 1000 s/mm2 (P 300 <0.001,P 500 =0.03 <0.05,P 800 =0.01 <0.05, P 1 000 =0.02<0.05).Conclusion Both SI and ADC value of DWI play important role in distinguishing benign and malignant SPNs, and the diagnostic efficiency of SI is superior to ADC value.