CAJ | 학술논문

目的：探讨红细胞分布宽度(RDW)对急性心力衰竭(AHF)近期预后的影响。方法选取急性心力衰竭入院的患者51例，正常对照组45例，于入院后24 h 内及10 d 后(死亡患者截止死亡前)进行 APACHE II 评分、检测 RDW、平均红细胞体积(MCV)、N 氨基末端脑钠肽(NT-proBNP)等指标，床旁心脏超声检测左心室射血分数(LVEF)，随访出院患者28 d 心血管事件(全因死亡、恶性心律失常、心力衰竭加重或再入院)发生情况。结果 AHF 患者的 RDW、NT-proBNP 均高于对照组，随着心功能不全加重而加重， Peason 相关分析显示 RDW 与 NT-proBNP、APACHE II 评分呈正相关，与 LVEF 呈负相关，其中 RDW 与 NT-proBNP 相关性更强。住院期间 RDW 动态变化与 AHF 患者28 d 主要心血管事件发生率有关。讨论 RDW 可以反映 AHF 危重程度，动态检测 RDW 对判断AHF 近期预后有意义，且高效、易得、费用低，值得推广。
목적：탐토홍세포분포관도(RDW)대급성심력쇠갈(AHF)근기예후적영향。방법선취급성심력쇠갈입원적환자51례，정상대조조45례，우입원후24 h 내급10 d 후(사망환자절지사망전)진행 APACHE II 평분、검측 RDW、평균홍세포체적(MCV)、N 안기말단뇌납태(NT-proBNP)등지표，상방심장초성검측좌심실사혈분수(LVEF)，수방출원환자28 d 심혈관사건(전인사망、악성심률실상、심력쇠갈가중혹재입원)발생정황。결과 AHF 환자적 RDW、NT-proBNP 균고우대조조，수착심공능불전가중이가중， Peason 상관분석현시 RDW 여 NT-proBNP、APACHE II 평분정정상관，여 LVEF 정부상관，기중 RDW 여 NT-proBNP 상관성경강。주원기간 RDW 동태변화여 AHF 환자28 d 주요심혈관사건발생솔유관。토론 RDW 가이반영 AHF 위중정도，동태검측 RDW 대판단AHF 근기예후유의의，차고효、역득、비용저，치득추엄。
Objective Prognosis of patients with acute heart failure by means of red blood cell distribution. Methods Select 51 cases admitted to hospital due to acute heart failure,45 normal as control group. Detecting APACHE II score、RDW、Mean Corpus-cular Volume(MCV)、N-terminal pro-B-type natriuretic peptide(NT-proBNP) before treatment and 10 days after treatment (before death for died patients), with ultrasound machine detecting ejection fraction in left ventricular(LVEF). All patients were followed up for 28 days, The major cardiovascular events( all causemortality, malignant arrhythmia, heart failurede-terioratedor re- admission) was observed. Results RDW, NT - proBNP in patients with AHF were higher than the control group,increased with poorer cardiac function. Peason correlation analysis show the RDW and NT - proBNPAPACHE II scores were positively correlated, negative correla-ted with LVEF, RDW have a better correlation with NT – proBNP,Hospitalization RDW dynamic changes related to 28 days major-cardioascular evnts in patients with AHF. Conclusion RDW can reflect the degree of AHF. Dynamic testing RDW is good for judging prognosis of AHF,RDW is kind of cheap, efficient and easy obtained measurement which is worth promoting.