CAJ | 학술논문

目的：分析腹腔热灌注与静脉化疗在晚期胃肠道肿瘤治疗的效果。方法选取我院曾收治的100例晚期胃肠道肿瘤患者，将其分成对照组和观察组，对照组患者采用单纯静脉化疗，观察组患者采用腹腔热灌注联合静脉化疗，观察患者在治疗期间所出现的不良反应，并对比两组患者的治疗效果。结果患者在治疗期间，均有不同程度上出现脱发、肝损伤、消化道不适、肾功能异常等不良反应，两组无差异（P>0.05）；治疗后，观察组患者的总有效率为78%，对照组患者的总有效率为46%，两组患者治疗效果差异具有统计学意义（P<0.05）。结论腹腔热灌注联合静脉化疗对晚期胃肠道肿瘤患者具有良好的治疗效果。
목적：분석복강열관주여정맥화료재만기위장도종류치료적효과。방법선취아원증수치적100례만기위장도종류환자，장기분성대조조화관찰조，대조조환자채용단순정맥화료，관찰조환자채용복강열관주연합정맥화료，관찰환자재치료기간소출현적불량반응，병대비량조환자적치료효과。결과환자재치료기간，균유불동정도상출현탈발、간손상、소화도불괄、신공능이상등불량반응，량조무차이（P>0.05）；치료후，관찰조환자적총유효솔위78%，대조조환자적총유효솔위46%，량조환자치료효과차이구유통계학의의（P<0.05）。결론복강열관주연합정맥화료대만기위장도종류환자구유량호적치료효과。
Objective To analyze the peritoneal perfusion with intravenous chemotherapy in advanced gastrointestinal efects of cancer treatment.MethodsOur hospital had treated 100 patients with advanced gastrointestinal cancer,were divided into a control group and observation group,control group were treated with intravenous chemotherapy alone,the observation group were treated with intraperitoneal hyperthermic perfusion combined with intravenous chemotherapy. Treatment adverse reactions that occurred was observed,and compared the therapeutic efect to two groups.ResultsThe patients during treatment,there were varying degrees of hair loss,liver damage,gastrointestinal discomfort,renal dysfunction and other adverse reactions,the diference was not significantly diferent (P> 0.05),after treatment,the total efective rate of patients in the observation group was 78%. The total efective rate was 46% in the control group,treatment groups were significantly different(P< 0.05),with statistical significance.Conclusion Intraperitoneal hyperthermic perfusion combined with intravenous chemotherapy in patients with advanced gastrointestinal tumors with a good therapeutic efect,in future clinical applications.