CAJ | 학술논문

癫(癎)性脑病为癫(癎)性异常本身引起的进行性脑功能障碍,主要包括起病于新生儿早期的早期肌阵挛脑病和大田原综合征,起病于婴儿期的West综合征和Dravet综合征,起病于婴儿和儿童早期的非进展性脑病中的肌阵挛持续状态,起病于儿童与青少年时期的Lennox-Gastaut综合征、Landau-Kleffner综合征和癫(癎)伴慢波睡眠期持续棘慢波.随着研究的深入,婴儿游走性局限性癫(癎)和伴多个独立棘波灶的严重癫(癎)也被推荐归纳入癫(癎)性脑病的范畴.现对癫(癎)性脑病的临床、病因、脑电图特点、治疗及预后进行综述.
전(간)성뇌병위전(간)성이상본신인기적진행성뇌공능장애,주요포괄기병우신생인조기적조기기진련뇌병화대전원종합정,기병우영인기적West종합정화Dravet종합정,기병우영인화인동조기적비진전성뇌병중적기진련지속상태,기병우인동여청소년시기적Lennox-Gastaut종합정、Landau-Kleffner종합정화전(간)반만파수면기지속극만파.수착연구적심입,영인유주성국한성전(간)화반다개독립극파조적엄중전(간)야피추천귀납입전(간)성뇌병적범주.현대전(간)성뇌병적림상、병인、뇌전도특점、치료급예후진행종술.
Epileptic encephalopathies are an epileptic condition characterized by epileptiform abnormalities associated with progressive cerebral dysfunction.These syndromes include early myoclonic encephalopathy and Ohtahara syndrome in the neonatal period,West syndrome and Dravet syndrome in infancy,myoclonic status in nonprogressive encephalopathies,and Lennox-Gastaut syndrome,Landau-Kleffner syndrome,and epilepsy with continuous spike waves during slow wave sleep in childhood and adolescences.Other epileptic syndromes such as migrating partial seizures in infancy and severe epilepsy with multiple independent spike foci may be reasonably added.In this paper,an overview of epileptic encephalopathies including clinical features,etiology,electroencephalogram characteristics,treatment and prognosis are provided.