CAJ | 학술논문

血管内皮生长因子(VEGF)对神经系统具有多重保护效应,涉及血管发生、神经发生、直接的神经营养保护作用以及抗凋亡等多种机制.大多数关于VEGF的神经系统疾病研究是其在肿瘤、外伤、卒中、自身免疫疾病及神经退行性疾病等方面,而关于VEGF在癫(癎)发作方面的研究相对少见,现就VEGF对癫(癎)发作的神经保护作用作一综述.
혈관내피생장인자(VEGF)대신경계통구유다중보호효응,섭급혈관발생、신경발생、직접적신경영양보호작용이급항조망등다충궤제.대다수관우VEGF적신경계통질병연구시기재종류、외상、졸중、자신면역질병급신경퇴행성질병등방면,이관우VEGF재전(간)발작방면적연구상대소견,현취VEGF대전(간)발작적신경보호작용작일종술.
Vascular endothelial growth factor (VEGF) have multiple protective effect on the nervous system which related to angiogenesis,neurogenesis,directly neurotrophic protection and antiapoptotic mechanisms.The study of the nervous system of VEGF focus on tumors,trauma,stroke,autoimmune diseases and neurodegenerative diseases.The study of VEGF related to epileptic seizures is relatively rare.This paper is to make a review about the neuroprotective effect of VEGF on epileptic seizure.