CAJ | 학술논문

目的：对原发性三叉神经痛作 X -刀大口径准直器及低剂量放射治疗的临床研究。方法应用 X -刀照射治疗原发性三叉神经痛患者95例，利用岩骨嵴三叉神经节压迹这一骨性标志选择靶点，10~13 mm 口径准直器，中心剂量17 Gy 推量至29 Gy，单次照射。结果在1~5个月缓解或消失，随着放疗剂量的加大，起效时间缩短，疼痛缓解效果较好；治愈37例，明显改善26例，有效18例，无效14例。5例病人在1个月内疼痛症状加重现象，2例分别于8，10个月后疼痛复发，经再次治疗后疼痛症状消失；全部病例均无并发症。结论岩骨嵴三叉神经节压迹这一骨性标志是原发性三叉神经痛放疗的可靠标志点，17Gy 是大口径准直器 X -刀治疗原发性三叉神经痛有效的剂量，29Gy 的治疗效果更好。
목적：대원발성삼차신경통작 X -도대구경준직기급저제량방사치료적림상연구。방법응용 X -도조사치료원발성삼차신경통환자95례，이용암골척삼차신경절압적저일골성표지선택파점，10~13 mm 구경준직기，중심제량17 Gy 추량지29 Gy，단차조사。결과재1~5개월완해혹소실，수착방료제량적가대，기효시간축단，동통완해효과교호；치유37례，명현개선26례，유효18례，무효14례。5례병인재1개월내동통증상가중현상，2례분별우8，10개월후동통복발，경재차치료후동통증상소실；전부병례균무병발증。결론암골척삼차신경절압적저일골성표지시원발성삼차신경통방료적가고표지점，17Gy 시대구경준직기 X -도치료원발성삼차신경통유효적제량，29Gy 적치료효과경호。
Objective:To study trigeminal neuralgia treated by X - ray knife using low dose and big diameter collima-tor. Methods:To treat 95 cases who have primary trigeminal neuralgia using X - ray knife ,10 ~ 13mm diameter collimator, 17Gy extend to 29Gy doses in the center by single irradiation. to select target using the trigeminal impression on the crista of petrosal bone. Results:Pain belief had disappeared for 37cases ,diminished significantly for 26 cases and effectively for 18cases in 1 ~ 5 monthes,14case were not effective. 5 cases aggravated in 1 month,2 cases had recurred after 8,10monthes respectively and been treated again whose pains disappeared;all cases had no complications. Conclusions:The trigeminal impression on the crista of petrosal bone is a dependable symbol for the treatment. 17GY is a effective dose for the treatment in large collimator and 29Gy is better.