中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2015年
6期
598-600
,共3页
方凌凌%王嵘%王斌%万伟庆
方凌凌%王嶸%王斌%萬偉慶
방릉릉%왕영%왕빈%만위경
脑底异常血管网病%成年人%工作记忆%注意力
腦底異常血管網病%成年人%工作記憶%註意力
뇌저이상혈관망병%성년인%공작기억%주의력
Moyamoya disease%Adult%Working memory%Attention
目的 探讨成年人烟雾病患者的工作记忆和注意力损害.方法 纳入首都医科大学附属北京天坛医院神经外科2014年4月至9月收住的成人烟雾病患者48例,同时纳入年龄、性别、教育程度、社会背景等相匹配的无脑部疾病48例志愿者为对照组.运用N-back、持续注意力反应测试(SART)评价受试者的视空间工作记忆及持续性注意力.结果 (1)N-back试验:烟雾病组和对照组比较,0-back试验中准确率分别为0.89 ±0.18、0.98 ±0.04,平均反应时间(RT)分别为(572±123)、(466±95) ms;1-back试验中准确率分别为0.55 ±0.23、0.72±0.20,RT分别为(763±232)、(750±202) ms;2-back试验中准确率分别为0.36±0.15、0.53±0.22,RT分别为(714±312)、(865±282)ms;除1-back的RT外,两组的其他指标比较,差异均有统计学意义(P ＜0.05);(2) SART试验:烟雾病组和对照组比较,击中率分别是0.88±0.19、0.98±0.03,RT分别为(458±112)、(382 ±91)ms,正确拒斥率分别为0.64±0.23、0.76±0.25,差异均有统计学意义(P＜0.05).结论 成人烟雾病患者存在视空间工作记忆及持续性注意力的损害.
目的 探討成年人煙霧病患者的工作記憶和註意力損害.方法 納入首都醫科大學附屬北京天罈醫院神經外科2014年4月至9月收住的成人煙霧病患者48例,同時納入年齡、性彆、教育程度、社會揹景等相匹配的無腦部疾病48例誌願者為對照組.運用N-back、持續註意力反應測試(SART)評價受試者的視空間工作記憶及持續性註意力.結果 (1)N-back試驗:煙霧病組和對照組比較,0-back試驗中準確率分彆為0.89 ±0.18、0.98 ±0.04,平均反應時間(RT)分彆為(572±123)、(466±95) ms;1-back試驗中準確率分彆為0.55 ±0.23、0.72±0.20,RT分彆為(763±232)、(750±202) ms;2-back試驗中準確率分彆為0.36±0.15、0.53±0.22,RT分彆為(714±312)、(865±282)ms;除1-back的RT外,兩組的其他指標比較,差異均有統計學意義(P ＜0.05);(2) SART試驗:煙霧病組和對照組比較,擊中率分彆是0.88±0.19、0.98±0.03,RT分彆為(458±112)、(382 ±91)ms,正確拒斥率分彆為0.64±0.23、0.76±0.25,差異均有統計學意義(P＜0.05).結論 成人煙霧病患者存在視空間工作記憶及持續性註意力的損害.
목적 탐토성년인연무병환자적공작기억화주의력손해.방법 납입수도의과대학부속북경천단의원신경외과2014년4월지9월수주적성인연무병환자48례,동시납입년령、성별、교육정도、사회배경등상필배적무뇌부질병48례지원자위대조조.운용N-back、지속주의력반응측시(SART)평개수시자적시공간공작기억급지속성주의력.결과 (1)N-back시험:연무병조화대조조비교,0-back시험중준학솔분별위0.89 ±0.18、0.98 ±0.04,평균반응시간(RT)분별위(572±123)、(466±95) ms;1-back시험중준학솔분별위0.55 ±0.23、0.72±0.20,RT분별위(763±232)、(750±202) ms;2-back시험중준학솔분별위0.36±0.15、0.53±0.22,RT분별위(714±312)、(865±282)ms;제1-back적RT외,량조적기타지표비교,차이균유통계학의의(P ＜0.05);(2) SART시험:연무병조화대조조비교,격중솔분별시0.88±0.19、0.98±0.03,RT분별위(458±112)、(382 ±91)ms,정학거척솔분별위0.64±0.23、0.76±0.25,차이균유통계학의의(P＜0.05).결론 성인연무병환자존재시공간공작기억급지속성주의력적손해.
Objective To investigate the working memory and attention impairment in adult patients with moyamoya disease.Methods Forty-eight adult patients with moyamoya disease admitted to the Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University from April 1,2014 to September 15,2014 were enrolled,and the age,sex,education,social background matched 48 normal healthy controls were also enrolled at the same time.N-back and sustaining attention reaction test (SART) were used to assess the visual-spatial working memory and sustained attention of the participants.Results (1) The N-back test:the moyamoya disease group compared with the control group,the accuracy rates in the 0-back test were 0.89 ±0.18 and 0.98 ±0.04 respectively; the mean response times (RT) were 572 ± 123 and 466 ±95 ms respectively; the accuracy rates in the 1-back test were 0.55 ±0.23 and 0.72 ±0.20 respectively ; RT were 763 ± 232 and 750 ± 202 ms respectively; the accuracy rates in the 2-back test were 0.36 ± 0.15 and 0.53 ± 0.22 respectively ; RT were 714 ± 312 and 865 ± 282 ms respectively ; in addition to RT of 1-back,there were significant differences in other indicators (P ＜ 0.05).(2) The SART test:the moyamoya disease group compared with the control group,the hit rats were 0.88 ± 0.19 and 0.98 ± 0.03 respectively; and RT were 458 ± 112 and 382 ±91 ms respectively.The correct rejection rates were 0.64 ±0.23 and 0.76 ± 0.25 respectively,and there was significant difference (P ＜ 0.05).Conclusions Adult patients with moyamoya disease had the visual-spatial working memory and sustaining attention impairment.
