CAJ | 학술논문

目的：目的定量综合评价饮水因素在食管癌发病过程中的作用。方法应用M eta分析方法对国内外有关不同类型饮用水与食管癌关系的研究进行定量综合分析，用固定效应模型或随机效应模型计算合并 OR值及其95％ C I。结果饮用自来水、清洁水与食管癌无关联性，合并效应值为0．73（0．44，1．20）；饮用未经处理水为食管癌的危险因素，合并效应值为1．73（1．27，2．37），其中饮用井水和沟塘水有统计学意义，合并效应值分别为1．48（1．23，1．79）和2．64（1．70，4．09），而饮用河水／湖水无统计学意义，合并效应值为1．09（0．56，2．10）。结论居民饮用未经处理的不洁水或污染水为食管癌的致癌因子。
목적：목적정량종합평개음수인소재식관암발병과정중적작용。방법응용M eta분석방법대국내외유관불동류형음용수여식관암관계적연구진행정량종합분석，용고정효응모형혹수궤효응모형계산합병 OR치급기95％ C I。결과음용자래수、청길수여식관암무관련성，합병효응치위0．73（0．44，1．20）；음용미경처리수위식관암적위험인소，합병효응치위1．73（1．27，2．37），기중음용정수화구당수유통계학의의，합병효응치분별위1．48（1．23，1．79）화2．64（1．70，4．09），이음용하수／호수무통계학의의，합병효응치위1．09（0．56，2．10）。결론거민음용미경처리적불길수혹오염수위식관암적치암인자。
Objective To evaluate the role of the water factors in the incidence of esophagus cancer .Methods Meta‐analysis was used to study the relationship of drinking water factors and esophageal cancer at home and a‐broad .Fixed effect model and random effect model were selected to calculate the pooled OR and its corresponding 95% .Results The association was not found in drinking tap water/clean water and esophageal cancer ,and the ORc was 0 .73 (0 .44 ,1 .20 ) .Untreated drinking water was a risk factor for esophageal cancer with the ORc 1 .73 (1 .27 ,2 .37) ,in which there was statistically significant differences of drinking ditch ponds and wells water with the ORc 2 .64 (1 .70 ,4 .09 )and 1 .48 (1 .23 ,1 .79 ) ,while we did not found significant difference of drinking river and lake water with its ORc 1 .09(0 .56 ,2 .10) .Conclusion Untreated or contaminated water were esophageal car‐cinogens .