CAJ | 학술논문

目的：了解某院药品不良反应（ADR）发生的特点及规律，为合理用药提供参考。方法收集某院2014年上报有效的167例ADR报告，通过Excel软件对ADR报告的主要内容进行统计、分析。结果167份ADR报告中，男性与女性比例为1∶2.09，多发于10岁以下的儿童；导致ADR的给药途径以静脉滴注（70.66%）和口服给药（24.55%）为主；涉及药品以抗微生物药居多（48.50%），其中又以头孢菌素类抗菌药物最为普遍；ADR最常见的临床表现为皮肤及其附件损害（43.11%）。结论进一步加强ADR监测及相关知识宣传的力度，以减少或避免ADR的重复发生。
목적：료해모원약품불량반응（ADR）발생적특점급규률，위합리용약제공삼고。방법수집모원2014년상보유효적167례ADR보고，통과Excel연건대ADR보고적주요내용진행통계、분석。결과167빈ADR보고중，남성여녀성비례위1∶2.09，다발우10세이하적인동；도치ADR적급약도경이정맥적주（70.66%）화구복급약（24.55%）위주；섭급약품이항미생물약거다（48.50%），기중우이두포균소류항균약물최위보편；ADR최상견적림상표현위피부급기부건손해（43.11%）。결론진일보가강ADR감측급상관지식선전적력도，이감소혹피면ADR적중복발생。
Objective To understand the adverse drug reactions(ADR)characteristics and rules in deel to provide reference for rational drug use. Methods We had colleted 167 effectively reported cases of ADR in our hospital from 2014,and had reported statistics analysis of the main content of the ADR by Excel software. Results In 167 cases of ADR,the ratio of male and female is 1∶2.09,multiple in the children who was less than 10 years old;lead to ADR of route of administration by intravenous infusion(70.66%)and oral administration(24.55%); the proportion of antimicrobial agents was 48.50%,among which the common clinical manifestations of ADR most came from the cephalosporins;the most ADR was the damage of skin and its appendages(43.11%). Conclusion To further strengthen the ADR monitoration and related knowledge propaganda,to reduce or avoid the repetition of ADR.