CAJ | 학술논문

目的：探讨应用分子生物学检测老年人腹泻病因的临床评价。方法随机收集2011年1～6月在南京某医院腹泻门诊就诊并临床诊断病毒性腹泻的60岁以上老年人的粪便20份，对诺如病毒、札幌病毒、轮状病毒、肠腺病毒和星状病毒进行分子生物学检测，并将检测结果与临床诊断进行比对，用于指导用药和治疗。结果20份随机样中共检测到13份阳性，其中有5份诺如病毒，4份轮状病毒，2份肠腺病毒，1份星状病毒，1份札幌病毒，病毒感染阳性率高达65％，加上由于技术原因不能检测到的病毒，该结果说明临床判断的准确性很高。结论确定病原后采取支持疗法，病人康复，避免了抗生素的使用。另外，札幌病毒感染老年人致腹泻在南京是首次报道。
목적：탐토응용분자생물학검측노년인복사병인적림상평개。방법수궤수집2011년1～6월재남경모의원복사문진취진병림상진단병독성복사적60세이상노년인적분편20빈，대낙여병독、찰황병독、륜상병독、장선병독화성상병독진행분자생물학검측，병장검측결과여림상진단진행비대，용우지도용약화치료。결과20빈수궤양중공검측도13빈양성，기중유5빈낙여병독，4빈륜상병독，2빈장선병독，1빈성상병독，1빈찰황병독，병독감염양성솔고체65％，가상유우기술원인불능검측도적병독，해결과설명림상판단적준학성흔고。결론학정병원후채취지지요법，병인강복，피면료항생소적사용。령외，찰황병독감염노년인치복사재남경시수차보도。
Objective To analyze the cause of diarrhea in the elderly,and to provide data for the treatment of age-related diarrhea. Methods From January 2011 to June 2011 in a hospital in Nanjing,20 fecal samples were randomly collected from outpatients who were clinical diagnosis of viral diarrhea in the elderly.Norovirus,sapporo virus,rotavirus,intestinal adenovirus and astrovirus were detected by mo-lecular biology and the detection results were compared with the clinical diagnosis and were used to guide medication and treatment.Results 13samplesweredetectedpositiveoutof20randomsamples,ofwhich5norovirus,4sapporovirus,2intestinaladenovirus,1astrovirus,1 sapporo virus,and virus-positive rate as high as 65%.Conclusions Supportive therapy should be applied to the patient after pathogenic de-termination and the patient are recovered without using antibiotics.In addition,this is the first report that the Sapporo virus infection-induced diarrhea in the elderly in Nanjing.