CAJ | 학술논문

目的：系统评价玄麦甘桔颗粒（胶囊）治疗慢性咽炎的疗效和安全性。方法计算机检索 Cochrane Library、PubMed、WHO ICTRP、CNKI、VIP、CBM和中国优秀硕士、博士学位毕业论文数据库的文献，检索时限均为从建库至2013年10月，由两名研究者按照纳入和排除标准独立进行文献筛选、资料提取、质量评价并交叉核对后，采用RevMan5.2软件进行Meta 分析。结果共纳入3个随机对照试验，合计420例慢性咽炎病患者，试验地点均在中国大陆，试验人群为中国人。各纳入研究的方法学质量总体较高。试验组为单用玄麦甘桔颗粒（胶囊），对照组为安慰剂、生活方式干预或其他西药（抗生素）。因纳入各研究两组药物的种类、剂量、患者病程、治疗疗程等方面均存在临床差异，故未进行合并分析，而分别报道了每个研究的结果。结论玄麦甘桔颗粒（胶囊）可以治疗慢性咽炎；玄麦甘桔颗粒（胶囊）治疗慢性咽炎的不良反应少且轻。目前玄麦甘桔颗粒（胶囊）治疗慢性咽炎临床研究的方法学和报告质量尚低，需要开展高质量的临床试验，以进一步证实玄麦甘桔颗粒（胶囊）治疗慢性咽炎的疗效。
목적：계통평개현맥감길과립（효낭）치료만성인염적료효화안전성。방법계산궤검색 Cochrane Library、PubMed、WHO ICTRP、CNKI、VIP、CBM화중국우수석사、박사학위필업논문수거고적문헌，검색시한균위종건고지2013년10월，유량명연구자안조납입화배제표준독립진행문헌사선、자료제취、질량평개병교차핵대후，채용RevMan5.2연건진행Meta 분석。결과공납입3개수궤대조시험，합계420례만성인염병환자，시험지점균재중국대륙，시험인군위중국인。각납입연구적방법학질량총체교고。시험조위단용현맥감길과립（효낭），대조조위안위제、생활방식간예혹기타서약（항생소）。인납입각연구량조약물적충류、제량、환자병정、치료료정등방면균존재림상차이，고미진행합병분석，이분별보도료매개연구적결과。결론현맥감길과립（효낭）가이치료만성인염；현맥감길과립（효낭）치료만성인염적불량반응소차경。목전현맥감길과립（효낭）치료만성인염림상연구적방법학화보고질량상저，수요개전고질량적림상시험，이진일보증실현맥감길과립（효낭）치료만성인염적료효。
Objective To evaluate the efficacy and safety of Xuan Mai Gan Jie particles (capsules)in the treatment of chronic pharyngitis. Methods We searched the Cochrane Library, literature retrieval time PubMed, WHO ICTRP, CNKI, VIP, CBM and China ’ s outstanding master’ s, doctorate thesis from the database are building a database to October 2013, according to the inclusion and by two researchers exclusion criteria were independently screened the literature, data extraction, quality assessment and cross-checked after using RevMan5.2 Meta-analysis software.Results A total of three randomized controlled trials, a total of 420 cases of patients with chronic pharyngitis, test locations are in China, the study population for the Chinese people.Each methodological quality of included studies generally high.The test group as a single particle with Xuan Mai Gan Jie ( capsules) , placebo control group, lifestyle intervention or other medicine ( antibiotics) .Because each study included two types of drug , dose, duration of disease, treatment, treatment and other aspects of clinical differences exist, it is not a merger analysis, and reported the results of each study .Conclusion Xuan Mai Gan Jie particles (capsules) to treat chronic pharyngitis; Xuan Mai Gan Jie particles (capsules) for the treatment of chronic pharyngitis fewer adverse reactions and light.Currently in clinical studies of chronic pharyngitis Xuan Mai Gan Jie particles ( capsules) therapy school and report quality is still low, the need for high-quality clinical trials to further confirm Xuan Mai Gan Jie particles ( capsules) therapy of chronic pharyngitis.