CAJ | 학술논문

目的：探讨正常高值血压者心血管危险因素对静息心率的影响。方法收集2013年5月至2014年6月在山西大医院体检中心检测的18～55岁正常高值血压者1599例，依据静息心率水平分为4组：静息心率<60次/min有345例，静息心率60～65次/min有370例，静息心率66～70次/min有448例，静息心率>70次/min有436例。记录其血压、年龄、静息心率、体质量指数、空腹血糖、血脂4项、肌酐、尿酸等心血管危险因素结果进行统计学分析。结果比较4组被研究者的收缩压、舒张压、年龄、体质量指数、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、肌酐、尿酸等指标差异有统计学意义（P<0.05）。Spearman相关分析显示：静息心率与体质量指数、空腹血糖、总胆固醇、低密度脂蛋白胆固醇、肌酐、尿酸呈显著正相关性；静息心率与年龄、高密度脂蛋白胆固醇呈显著负相关性。多重线性分析（α入=0.05，α出=0.10的纳入排出标准显示，对静息心率影响因素依次为总胆固醇、低密度脂蛋白胆固醇、体质量指数、年龄、甘油三酯、尿酸和空腹血糖。结论正常高值血压人群中静息心率与多种心血管危险因素之间存在密切联系，心血管交感神经激活可能解释这种关系。
목적：탐토정상고치혈압자심혈관위험인소대정식심솔적영향。방법수집2013년5월지2014년6월재산서대의원체검중심검측적18～55세정상고치혈압자1599례，의거정식심솔수평분위4조：정식심솔<60차/min유345례，정식심솔60～65차/min유370례，정식심솔66～70차/min유448례，정식심솔>70차/min유436례。기록기혈압、년령、정식심솔、체질량지수、공복혈당、혈지4항、기항、뇨산등심혈관위험인소결과진행통계학분석。결과비교4조피연구자적수축압、서장압、년령、체질량지수、공복혈당、총담고순、감유삼지、고밀도지단백담고순、저밀도지단백담고순、기항、뇨산등지표차이유통계학의의（P<0.05）。Spearman상관분석현시：정식심솔여체질량지수、공복혈당、총담고순、저밀도지단백담고순、기항、뇨산정현저정상관성；정식심솔여년령、고밀도지단백담고순정현저부상관성。다중선성분석（α입=0.05，α출=0.10적납입배출표준현시，대정식심솔영향인소의차위총담고순、저밀도지단백담고순、체질량지수、년령、감유삼지、뇨산화공복혈당。결론정상고치혈압인군중정식심솔여다충심혈관위험인소지간존재밀절련계，심혈관교감신경격활가능해석저충관계。
Objective To investigate the high normal blood pressure on cardiovascular risk factors influencing resting heart rate. Methods Collection in 2013 May to 2014 June in hospital of 1599 patients aged 18 to 55 years old people with high normal blood pressure. On the basis of resting heart rate and divided into 4 groups:Group A(Resting heart rate<60/min,n=345);Group B(Resting heart rate60~65/min,n=370);Group C(Resting heart rate65~70 /min,n=448);Group D(Resting heart rate>70 /min,n=436). Recording Cardiovascular risk of blood pressure and age,resting heart rate,body mass index,fasting blood glucose,four blood lipids,creatinine,uric acid and other factors the results of statistical analysis. Results Comparison of 4 groups of subjects of systolic blood pressure,diastolic blood pressure, age,body mass index,fasting blood glucose,total cholesterol,triglycerides,high density lipoprotein protein cholesterol,low density lipoprotein cholesterol,creatinine,uric acid and other indicators have difference in Statistics (P<0.05). Spearman correlation analysis showed that the resting heart rate and body mass index,fasting blood glucose,total cholesterol,low density lipoprotein cholesterol,creatinine,uric acid had a significant positive correlation. Resting heart rate and age,high density lipoprotein cholesterol was significantly negative correlation. Multiple linear analysis (alpha into =0.05,alpha =0.10 into the discharge standard) showed the influencing factors of the resting heart rate followed by total cholesterol,low density lipoprotein cholesterol,body mass index,age,triglyceride,uric acid and fasting blood glucose. Conclusion There is a close relationship between the high normal resting blood pressure heart rate with multiple cardiovascular risk factors and cardiovascular sympathetic activation may explain this relationship.