中国卫生产业
中國衛生產業
중국위생산업
CHINA HEALTH INDUSTRY
2015年
9期
194-195,198
,共3页
介入手术%医院感染%细菌分布%耐药性
介入手術%醫院感染%細菌分佈%耐藥性
개입수술%의원감염%세균분포%내약성
Interventional operation%Nosocomial infection%Bacterial distribution%Drug resistance
目的：了解介入治疗术后患者医院感染的常见病原菌分布及耐药情况，为临床合理使用抗菌药物，控制医院感染提供科学依据。方法回顾性调查医院2008年3月要2014年3月介入手术后患者医院感染的临床现状，统计分析225株病原菌的药敏试验结果。结果分离的225株病原菌中革兰阴性杆菌138株，占61.3%，主要为大肠埃希菌(25.8%)，铜绿假单胞菌(19.1%)和鲍氏不动杆菌(8.9%)；革兰阳性球菌79株，占35.1%，主要为金黄色葡萄球菌(15.6%)及凝固酶阴性葡萄球菌(11.5%)；真菌8株，占3.6%。药敏试验结果显示分离的多数细菌耐药性均较高，大肠埃希菌和铜绿假单胞菌对常用的抗菌药物氨苄西林和头孢类的耐药率均大于60.0%，对亚胺培南、阿米卡星和妥布霉素的耐药率较低，均小于20.0%；金黄色葡萄球菌和凝固酶阴性葡萄球菌对万古霉素和替考拉宁均较敏感，尤其是对万古霉素100%敏感，而对青霉素、氨苄西林、红霉素、环丙沙星、克林霉素和左氧氟沙星的耐药率较高，均大于50.0%。结论条件致病菌已成为介入手术后患者医院感染的重要病原菌，临床医师应严格按照细菌学培养及药敏试验结果合理应用抗菌药物，采取有效措施积极预防和控制医院感染。
目的：瞭解介入治療術後患者醫院感染的常見病原菌分佈及耐藥情況，為臨床閤理使用抗菌藥物，控製醫院感染提供科學依據。方法迴顧性調查醫院2008年3月要2014年3月介入手術後患者醫院感染的臨床現狀，統計分析225株病原菌的藥敏試驗結果。結果分離的225株病原菌中革蘭陰性桿菌138株，佔61.3%，主要為大腸埃希菌(25.8%)，銅綠假單胞菌(19.1%)和鮑氏不動桿菌(8.9%)；革蘭暘性毬菌79株，佔35.1%，主要為金黃色葡萄毬菌(15.6%)及凝固酶陰性葡萄毬菌(11.5%)；真菌8株，佔3.6%。藥敏試驗結果顯示分離的多數細菌耐藥性均較高，大腸埃希菌和銅綠假單胞菌對常用的抗菌藥物氨芐西林和頭孢類的耐藥率均大于60.0%，對亞胺培南、阿米卡星和妥佈黴素的耐藥率較低，均小于20.0%；金黃色葡萄毬菌和凝固酶陰性葡萄毬菌對萬古黴素和替攷拉寧均較敏感，尤其是對萬古黴素100%敏感，而對青黴素、氨芐西林、紅黴素、環丙沙星、剋林黴素和左氧氟沙星的耐藥率較高，均大于50.0%。結論條件緻病菌已成為介入手術後患者醫院感染的重要病原菌，臨床醫師應嚴格按照細菌學培養及藥敏試驗結果閤理應用抗菌藥物，採取有效措施積極預防和控製醫院感染。
목적：료해개입치료술후환자의원감염적상견병원균분포급내약정황，위림상합리사용항균약물，공제의원감염제공과학의거。방법회고성조사의원2008년3월요2014년3월개입수술후환자의원감염적림상현상，통계분석225주병원균적약민시험결과。결과분리적225주병원균중혁란음성간균138주，점61.3%，주요위대장애희균(25.8%)，동록가단포균(19.1%)화포씨불동간균(8.9%)；혁란양성구균79주，점35.1%，주요위금황색포도구균(15.6%)급응고매음성포도구균(11.5%)；진균8주，점3.6%。약민시험결과현시분리적다수세균내약성균교고，대장애희균화동록가단포균대상용적항균약물안변서림화두포류적내약솔균대우60.0%，대아알배남、아미잡성화타포매소적내약솔교저，균소우20.0%；금황색포도구균화응고매음성포도구균대만고매소화체고랍저균교민감，우기시대만고매소100%민감，이대청매소、안변서림、홍매소、배병사성、극림매소화좌양불사성적내약솔교고，균대우50.0%。결론조건치병균이성위개입수술후환자의원감염적중요병원균，림상의사응엄격안조세균학배양급약민시험결과합리응용항균약물，채취유효조시적겁예방화공제의원감염。
Objective To investigate the clinical distribution and drug resistance of pathogens causing infections in patients of in-terventional operation,to provide the scientific evidence for clinical controlling of them. Methods The clinical status of pathogens causing infections in patients of interventional operation from Mar. 2008 to Mar. 2014 was investigated retrospectively. The suscep-tibility testing results of 225 cases were analyzed statistically. Results Of 225 strains of pathogens isolated,including 138 (61.3%) stains of gram-negative bacilli,Escherichia coli(25.8%), Pseudomonas aeruginosa(19.1%)and Acinetobacter baumannii(8.9%)were the most common gram-negative bacteria;79(35.1%) stains of gram-positive bacilli,Staphylococcus aureus(15.6%) and co-agulase-negative Staphylococcus(11.5%)were the most common gram-positive bacteria;8(3.6%) stains of fungus.the drug suscepti-bility testing demonstrated that the drug resistance of most of the pathogens was high,the drug-resistance rates of Escherichia coli(25.8%)and Pseudomonas aeruginosa to ampicillin and cephalosporins were all above 60.0%,to imipenem, amikacin and o-bramycin were all less than 20.0%;Staphylococcus aureus and coagulase-negative Staphylococcus were susceptible to vancomycin and teicoplanin,100%sensitive to vancomycin,the resistance rate to penicillin,ampicillin,erythromycin,ciprofloxacin,clindamycin and levofloxacin were all above 50.0%. Conclusion The opportunistic pathogens has become the major pathogens of interventional operation patients with hospital infection,The clinical should prescribe the antibiotics reasonably according to etiology,take effec-tive measures to prevent and control infection.
