CAJ | 학술논문

目的：探讨血管内支架成形术治疗动脉粥样硬化性血管狭窄导致的短暂性脑缺血发作（TIA）的疗效与安全性。方法：选择2011年1月至2013年2月间我院收治的血管狭窄导致的TIA患者100例为研究对象，均分成联合治疗组（血管内支架形成术与药物联合治疗）和常规（药物）治疗组。治疗12个月后，比较两组患者TIA复发及卒中的发生率、治疗前后的血管狭窄率。结果：与治疗前比较，治疗后常规治疗组无明显差异，联合治疗组患者血管狭窄率明显降低[（73.31±12.76）％比（25.01±5.73）％]，且显著低于常规治疗组（74.33±12.96）％， P均＜0.01；在随访的12个月期间，与常规治疗组相比，联合治疗组患者出现复发 TIA （16.0％比2.0％）和脑卒中（12.0％比0）的比例显著降低（P均＜0.05）。结论：血管内支架形成术可以明显提高动脉粥样硬化性血管狭窄患者的疗效，有效地改善预后，适宜在一定情况下临床推广。
목적：탐토혈관내지가성형술치료동맥죽양경화성혈관협착도치적단잠성뇌결혈발작（TIA）적료효여안전성。방법：선택2011년1월지2013년2월간아원수치적혈관협착도치적TIA환자100례위연구대상，균분성연합치료조（혈관내지가형성술여약물연합치료）화상규（약물）치료조。치료12개월후，비교량조환자TIA복발급졸중적발생솔、치료전후적혈관협착솔。결과：여치료전비교，치료후상규치료조무명현차이，연합치료조환자혈관협착솔명현강저[（73.31±12.76）％비（25.01±5.73）％]，차현저저우상규치료조（74.33±12.96）％， P균＜0.01；재수방적12개월기간，여상규치료조상비，연합치료조환자출현복발 TIA （16.0％비2.0％）화뇌졸중（12.0％비0）적비례현저강저（P균＜0.05）。결론：혈관내지가형성술가이명현제고동맥죽양경화성혈관협착환자적료효，유효지개선예후，괄의재일정정황하림상추엄。
Objective:To explore therapeutic effect and safety of endovascular stenting on transient ischemic attack (TIA) caused by atherosclerotic vascular stenosis .Methods:A total of 100 patients with TIA caused by vascular ste-nosis in our hospital from Jan 2011 to Feb 2013 were enrolled ,and equally divided into combined treatment group (received endovascular stenting combined medication ) and routine treatment group (received medication treat-ment) .After 12-month treatment ,recurrence rate of TIA ,incidence rate of stroke and vascular stenosis rate before and after treatment were compared between two groups .Results:Compared with before treatment ,there was no significant change in all above-stated indexes after treatment in routine treatment group;were significant reduction in vascular restenosis rate [ (73.31 ± 12.76)% vs .(25.01 ± 5.73)% ] in combined treatment group ,and it signifi-cantly reduced than that of routine treatment group (74.33 ± 12.96)% ,P<0.01 both ;during the 12-month follow-up ,compared with routine treatment group , there were significant reductions in percentages of recurrent TIA (16.0% vs .2.0% ) and cerebral stroke (12.0% vs .0) in combined treatment group ,P<0.05 both Conclusion:En-dovascular stenting can significantly improve clinical therapeutic effect and prognosis in patients with atherosclerotic vascular stenosis ,and is worth clinical extension in some condition .