医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
16期
7-8,9
,共3页
龚芫(综述)%吴瑞瑾(审校)
龔芫(綜述)%吳瑞瑾(審校)
공원(종술)%오서근(심교)
子宫内膜息肉%高危因素%发病机制
子宮內膜息肉%高危因素%髮病機製
자궁내막식육%고위인소%발병궤제
Endometrial polyps%Risk factors%Pathogenesis
子宫内膜息肉是女性常见的子宫内膜病变,其发生原因和发病机制至今尚未清楚。EP的发病机制涉及激素、炎症、凋亡、基因等多因素,而与发病相关高危因素包括绝经、肥胖、激素替代治疗等,但都尚未定论。该文将从子宫内膜息肉发病相关的多种高危因素做一综述,更全面、准确地揭示子宫内膜息肉发生的特点,以更好地指导进一步的临床实验研究及疾病的预防和治疗。
子宮內膜息肉是女性常見的子宮內膜病變,其髮生原因和髮病機製至今尚未清楚。EP的髮病機製涉及激素、炎癥、凋亡、基因等多因素,而與髮病相關高危因素包括絕經、肥胖、激素替代治療等,但都尚未定論。該文將從子宮內膜息肉髮病相關的多種高危因素做一綜述,更全麵、準確地揭示子宮內膜息肉髮生的特點,以更好地指導進一步的臨床實驗研究及疾病的預防和治療。
자궁내막식육시녀성상견적자궁내막병변,기발생원인화발병궤제지금상미청초。EP적발병궤제섭급격소、염증、조망、기인등다인소,이여발병상관고위인소포괄절경、비반、격소체대치료등,단도상미정론。해문장종자궁내막식육발병상관적다충고위인소주일종술,경전면、준학지게시자궁내막식육발생적특점,이경호지지도진일보적림상실험연구급질병적예방화치료。
Endometrial polyp(EP) is one of the most common endometrial diseases in women. The pathogenesis of EP is still unknown, neither are the risk factors. Hormone level, chronic inflammation, cell apoptosis and gene mutation are considered involving in the pathogenic processes. Postmenopausal status, overweight/obesity and hormone replacement therapy have been suggested as related factors of EP. The accurate mechanism remains unclear.This is a review about risk factors and related mechanism of EP.