中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
11期
39-40
,共2页
通冠胶囊%急性心肌梗死%炎性反应%心功能影响
通冠膠囊%急性心肌梗死%炎性反應%心功能影響
통관효낭%급성심기경사%염성반응%심공능영향
Tongguan capsule%Acute myocardial infarction%Inflammation%Cardiac function
目的 探讨急性心肌梗死采用通冠胶囊治疗对炎性反应及心功能的影响.方法 选取修武县人民医院2013年5月至2014年5月收治的100例急性心肌梗死患者作研究对象,随机分为常规治疗组(对照组,n=50)与加用通冠胶囊治疗组(观察组,n=50),观察通冠胶囊对炎性反应及心功能的影响.结果 两组治疗前超氧化物歧化酶(SOD)、丙二醛(MDA)、N末端脑钠肽前体(NT-proBNP)、C-反应蛋白(CRP)比较差异均未见统计学意义(P＞0.05),治疗后SOD水平升高(P＜0.05),NT-proBNP、MDA、CRP降低(P＜0.05).观察组治疗后SOD升高幅度优于对照组,NT-proBNP、MDA、CRP降低幅度优于对照组,差异有统计学意义(P＜0.05).两组治疗前心脏指数(CI)、心输出量(C0)、左室射血分数(LVEF)比较差异均未见统计学意义(P＞0.05),治疗后均显著增加(P＜0.05),观察组心功能好转幅度优于对照组(P＜0.05).结论 急性心肌梗死患者采用通冠胶囊治疗,可使机体炎性反应降低,清除氧自由基损伤能力增加,促使心功能改善,进而保障预后,具有非常积极的临床价值.
目的 探討急性心肌梗死採用通冠膠囊治療對炎性反應及心功能的影響.方法 選取脩武縣人民醫院2013年5月至2014年5月收治的100例急性心肌梗死患者作研究對象,隨機分為常規治療組(對照組,n=50)與加用通冠膠囊治療組(觀察組,n=50),觀察通冠膠囊對炎性反應及心功能的影響.結果 兩組治療前超氧化物歧化酶(SOD)、丙二醛(MDA)、N末耑腦鈉肽前體(NT-proBNP)、C-反應蛋白(CRP)比較差異均未見統計學意義(P＞0.05),治療後SOD水平升高(P＜0.05),NT-proBNP、MDA、CRP降低(P＜0.05).觀察組治療後SOD升高幅度優于對照組,NT-proBNP、MDA、CRP降低幅度優于對照組,差異有統計學意義(P＜0.05).兩組治療前心髒指數(CI)、心輸齣量(C0)、左室射血分數(LVEF)比較差異均未見統計學意義(P＞0.05),治療後均顯著增加(P＜0.05),觀察組心功能好轉幅度優于對照組(P＜0.05).結論 急性心肌梗死患者採用通冠膠囊治療,可使機體炎性反應降低,清除氧自由基損傷能力增加,促使心功能改善,進而保障預後,具有非常積極的臨床價值.
목적 탐토급성심기경사채용통관효낭치료대염성반응급심공능적영향.방법 선취수무현인민의원2013년5월지2014년5월수치적100례급성심기경사환자작연구대상,수궤분위상규치료조(대조조,n=50)여가용통관효낭치료조(관찰조,n=50),관찰통관효낭대염성반응급심공능적영향.결과 량조치료전초양화물기화매(SOD)、병이철(MDA)、N말단뇌납태전체(NT-proBNP)、C-반응단백(CRP)비교차이균미견통계학의의(P＞0.05),치료후SOD수평승고(P＜0.05),NT-proBNP、MDA、CRP강저(P＜0.05).관찰조치료후SOD승고폭도우우대조조,NT-proBNP、MDA、CRP강저폭도우우대조조,차이유통계학의의(P＜0.05).량조치료전심장지수(CI)、심수출량(C0)、좌실사혈분수(LVEF)비교차이균미견통계학의의(P＞0.05),치료후균현저증가(P＜0.05),관찰조심공능호전폭도우우대조조(P＜0.05).결론 급성심기경사환자채용통관효낭치료,가사궤체염성반응강저,청제양자유기손상능력증가,촉사심공능개선,진이보장예후,구유비상적겁적림상개치.
Objective To investigate the influence of Tongguan capsule on inflammation and cardiac function of acute myocardial infarction.Methods From May 2013 to May 2015,100 cases of acute myocardial infarction in Xiuwu people' s hospital were randomly divided into conventional therapy group (control group,n =50) and with the addition of Tongguan capsule in treatment group (observation group,n =50),and the effects on inflammation and cardiac function were observed.Results SOD,MDA,NT-proBNP,CRP values of the two groups before treatment had no significant differences (P ＞ 0.05) ; after treatment,SOD levels increased(P ＜ 0.05) and NT-proBNP,MDA,CRP decreased (P ＜ 0.05).After treatment,SOD increased significantly and NT-proBNP,MDA,CRP decreased significantly in the observation group than that in the control group,there were significant differences(P ＜ 0.05).Before treatment,CI,CO,LVEF had no significant differences between the two groups (P ＞ 0.05),they were all significantly increased after treatment (P ＜ 0.05).The heart function improved significantly in observation group than that in the control group (P ＜ 0.05).Conclusions Tongguan capsule in the treatment of patients with acute myocardial infarction can reduce the body' s inflammatory response,increase the ability to scavenge oxygen free radical damage,prompt heart function improved,and thus protect the prognosis,has a very positive clinical value.
