CAJ | 학술논문

目的：探讨患者糖化血红蛋白（ HbA1 c ）与急性冠脉综合征发生和发展及危险严重程度的关系。方法选取急性冠脉综合征患者526例和正常对照者82例。比较不同急性冠脉综合征类型、冠脉狭窄程度及急性冠脉综合征危险风险程度组间HbA1c水平，探讨HbA1c与急性冠脉综合征的发生发展、冠脉严重程度及危险程度的相关性。结果 ST段抬高型急性冠脉综合征（ STEMI）患者和非ST段抬高型急性冠脉综合征（NSTEMI）患者HbA1c水平明显高于正常组（P＜0.05）。随着冠脉病变程度不断加重，HbA1c水平逐渐增高（P＜0.05）；随着冠心病危险程度不断增加，HbA1c水平逐渐增高（P＜0.05）。结论随着冠脉病变程度加重HbA1c水平呈升高趋势。血清HbA1c水平与冠心病危险程度关系密切，是急性冠脉综合征危险程度加重的因素。
목적：탐토환자당화혈홍단백（ HbA1 c ）여급성관맥종합정발생화발전급위험엄중정도적관계。방법선취급성관맥종합정환자526례화정상대조자82례。비교불동급성관맥종합정류형、관맥협착정도급급성관맥종합정위험풍험정도조간HbA1c수평，탐토HbA1c여급성관맥종합정적발생발전、관맥엄중정도급위험정도적상관성。결과 ST단태고형급성관맥종합정（ STEMI）환자화비ST단태고형급성관맥종합정（NSTEMI）환자HbA1c수평명현고우정상조（P＜0.05）。수착관맥병변정도불단가중，HbA1c수평축점증고（P＜0.05）；수착관심병위험정도불단증가，HbA1c수평축점증고（P＜0.05）。결론수착관맥병변정도가중HbA1c수평정승고추세。혈청HbA1c수평여관심병위험정도관계밀절，시급성관맥종합정위험정도가중적인소。
Objective To explore the relationship between HbA1c and the occurrence, development and the risk degree of acute coronary syndrome( ACS) .Methods 526 patients with ACS were collected as ACS group and 82 healthy people were taken as the control group.HbA1c levels were compared in different types of ACS, severities of coronary artery stenosis and the risk levels to explore the correlation between HbA1c and the occurrence, develop-ment, and the risk degree of ACS.Results HbA1c levels in both STEMI and NSTEMI patients were significantly greater in the ACS group than those in the control group(P<0.05).HbA1c levels were gradually increased with both the constantly worsened conditions and the rising risk degrees of coronary heart diseases ( P<0.05 ) .Conclusion HbA1c levels show a trend of increasing with the aggravation of coronary artery diseases.Serum HbA1c level is close-ly connected with the risk degree of coronary heart diseases, therefore, is a factor of the aggravation of the risk degree of ACS.