CAJ | 학술논문

目的：对该地区无偿献血者的不规则抗体进行回顾性分析，以期发现其中的规律，确保临床输血安全和有效。方法收集2011年2月至2012年12月深圳地区169860例无偿献血者的标本，用特定抗原的红细胞，通过盐水法检测不规则抗体，阳性标本由血型室鉴定抗体特异性。结果169860份无偿献血者不规则抗体阳性36例（0．021％），其中抗‐M 阳性12例，抗‐D阳性4例，抗‐P1阳性1例，抗‐A1阳性2例，冷抗体1例，抗‐M合并其他不规则抗体1例，未知其特异性抗体15例；男性不规则抗体阳性率0．013％（15／118723），女性不规则抗体阳性率0．041％（21／51137）。结论女性的献血者不规则抗体的阳性率高于男性献血者，且该地区的献血者不规则抗体阳性检出率偏低，需要结合其他不规则抗体的检出方法，提高其检出率，确保输血的安全有效。
목적：대해지구무상헌혈자적불규칙항체진행회고성분석，이기발현기중적규률，학보림상수혈안전화유효。방법수집2011년2월지2012년12월심수지구169860례무상헌혈자적표본，용특정항원적홍세포，통과염수법검측불규칙항체，양성표본유혈형실감정항체특이성。결과169860빈무상헌혈자불규칙항체양성36례（0．021％），기중항‐M 양성12례，항‐D양성4례，항‐P1양성1례，항‐A1양성2례，랭항체1례，항‐M합병기타불규칙항체1례，미지기특이성항체15례；남성불규칙항체양성솔0．013％（15／118723），녀성불규칙항체양성솔0．041％（21／51137）。결론녀성적헌혈자불규칙항체적양성솔고우남성헌혈자，차해지구적헌혈자불규칙항체양성검출솔편저，수요결합기타불규칙항체적검출방법，제고기검출솔，학보수혈적안전유효。
Objective To retrospectively analyse the irregular antibodies of the local blood donors ,in order to find the rules ,To ensure the safety and effectiveness of clinical blood transfusion .Methods Collected 169 860 blood donors specimens with the spe‐cific antigen of red blood cells in Shenzhen area from February 2011 to December 2012 ,through Brine method for detection of irreg‐ular antibodies ,positive samples would be identified the specificity of antibodies in blood typing department .Results 169 860 healthy blood donors of irregular antibodies were positive in 36 cases(0 .021% ) ,with 12 cases anti‐M ,4 cases anti‐D ,1 case anti‐P1 ,2 cases anti‐A1 ,1 case of cold antibody ,anti‐M with other irregular antibody in 1 cases ;Male irregular antibody positive rate was 0 .013% (15/118 723) ,female irregular antibody positive rate was 0 .041% (21/51 137) .Conclusion The positive rate of irregular antibody in female blood donors is higher than male blood donors ,and the positive rate of irregular antibody of blood donors is low in this area ,which need to be combined with other irregular antibody detection method to improve the detection rate and ensure the safety and effective of blood transfusion .