CAJ | 학술논문

目的：应用图像引导放射治疗（Image—guided radiotherapy， IGRT）技术，观察膀胱、直肠在治疗中的变化，分析其对治疗的影响。方法：入选16例接受根治性调强放疗的前列腺癌患者，共行KV－CBCT在线校正治疗体位214次。在模拟CT和锥形束CT （ cone beam CT， CBCT）图像上勾画CTV、膀胱及直肠，观察膀胱、直肠体积和位置变化，分析其对治疗的影响。结果：治疗过程中膀胱和直肠的充盈度有较大变化。 PTV95与膀胱、直肠的移动具有相关性，相关系数分别为0.293、0.171。直肠体积与PTV95的相关系数为0.112，说明两者存在一定相关性。对于PTVmin而言，除上述各指标之外，与膀胱体积有一定相关性，相关系数为－0.126。结论：在前列腺癌的调强治疗中，使膀胱、直肠尤其是后者尽量复原定位时状态，对保证靶区受量及减少直肠受照有明显意义。
목적：응용도상인도방사치료（Image—guided radiotherapy， IGRT）기술，관찰방광、직장재치료중적변화，분석기대치료적영향。방법：입선16례접수근치성조강방료적전렬선암환자，공행KV－CBCT재선교정치료체위214차。재모의CT화추형속CT （ cone beam CT， CBCT）도상상구화CTV、방광급직장，관찰방광、직장체적화위치변화，분석기대치료적영향。결과：치료과정중방광화직장적충영도유교대변화。 PTV95여방광、직장적이동구유상관성，상관계수분별위0.293、0.171。직장체적여PTV95적상관계수위0.112，설명량자존재일정상관성。대우PTVmin이언，제상술각지표지외，여방광체적유일정상관성，상관계수위－0.126。결론：재전렬선암적조강치료중，사방광、직장우기시후자진량복원정위시상태，대보증파구수량급감소직장수조유명현의의。
Objective: To observe the motions of normal tissues and organs, and analyze their impact on treatment by using image-guided radiotherapy ( IGRT) .Metheds: 16 patients with prostate cancer undergoing IMRT were enrolled onto the study and 214 CBCT imagings were obtained from this study.The CTV, bladder and rectum were contoured on all CT scans to examine their volume and position changes, and to evaluate their impact on the treatment.Results: Volumes of the bladder and rectum were observed to have a relatively significant variation during the treatment.There are correlations between PTV95 and the motions of bladder and rec-tum, correlation coefficients were 0.293 and 0.171.The correlation coefficient of rectal volume and PTV95 was 0.112, that there is a certain correlation.For PTVmin, in addition to the above indexes, and there is a certain correlation between bladder volume, the corre-lation coefficient is -0.126.Conclusions: The state recovery when positioning of bladder and rectum especially the latter has obvious significance to ensure the target dose and reduce exposure of rectum for image guided prostate radiotherapy.