中国医学影像学杂志
中國醫學影像學雜誌
중국의학영상학잡지
CHINESE JOURNAL OF MEDICAL IMAGING
2015年
6期
423-427
,共5页
马芸%李晓光%黄杰%康厚艺%张伟国
馬蕓%李曉光%黃傑%康厚藝%張偉國
마예%리효광%황걸%강후예%장위국
星形细胞瘤%脑肿瘤%磁共振成像%扩散加权成像%扩散张量成像%磁共振波谱学%灌注成像%诊断,鉴别
星形細胞瘤%腦腫瘤%磁共振成像%擴散加權成像%擴散張量成像%磁共振波譜學%灌註成像%診斷,鑒彆
성형세포류%뇌종류%자공진성상%확산가권성상%확산장량성상%자공진파보학%관주성상%진단,감별
Astrocytoma%Brain neoplasms%Magnetic resonance imaging%Diffusion weighted imaging%Diffusion tensor imaging%Magnetic resonance spectroscopy%Perfusion imaging%Diagnosis,differential
目的探讨毛细胞型星形细胞瘤(PA)的磁共振灌注成像(PWI)、扩散加权成像(DWI)、磁共振波谱成像(MRS)和磁敏感加权成像(SWI)的影像学特点,提高对本病的诊断准确性。资料与方法回顾性分析11例经手术病理证实的 PA 的MRI 表现,分析其常规 MRI 及生理代谢成像特点。结果完全为囊性或实性病变各1例,其余9例为囊实性病变;10例病变表现为混杂长 T1长 T2信号,FLAIR 呈混杂高信号;1例表现为均匀长 T1长 T2信号,FLAIR 呈高信号;增强扫描病变实性部分和囊壁及壁结节均呈明显强化,6例为花状样强化,3例为结节状和花环状强化,1例为明显强化,1例为轻度环形强化;3例 SWI 表现为片状低信号,2例为点状低信号,2例未见低信号显示,其平均肿瘤内低信号分级为1.57级。PWI 表现为高灌注,其最大相对脑血容量为2.64±1.22。肿瘤实性部分胆碱(Cho)明显升高,N-乙酰天门冬氨酸(NAA)明显降低,Cho/NAA 比值为5.13±4.72(1.46~15.26),5例出现乳酸峰增高。DWI 示1例实性病例可见明显扩散受限,其余7例囊实性病例均未见明显扩散受限,其平均相对 ADC 值为1.60±0.58。结论 PA 符合低级别胶质瘤的绝大多数影像学表现,但其 MRI 生理代谢成像有一定的特征性,其灌注明显高于同级别的胶质瘤,正确认识其表现有助于提高诊断和鉴别诊断的准确性。
目的探討毛細胞型星形細胞瘤(PA)的磁共振灌註成像(PWI)、擴散加權成像(DWI)、磁共振波譜成像(MRS)和磁敏感加權成像(SWI)的影像學特點,提高對本病的診斷準確性。資料與方法迴顧性分析11例經手術病理證實的 PA 的MRI 錶現,分析其常規 MRI 及生理代謝成像特點。結果完全為囊性或實性病變各1例,其餘9例為囊實性病變;10例病變錶現為混雜長 T1長 T2信號,FLAIR 呈混雜高信號;1例錶現為均勻長 T1長 T2信號,FLAIR 呈高信號;增彊掃描病變實性部分和囊壁及壁結節均呈明顯彊化,6例為花狀樣彊化,3例為結節狀和花環狀彊化,1例為明顯彊化,1例為輕度環形彊化;3例 SWI 錶現為片狀低信號,2例為點狀低信號,2例未見低信號顯示,其平均腫瘤內低信號分級為1.57級。PWI 錶現為高灌註,其最大相對腦血容量為2.64±1.22。腫瘤實性部分膽堿(Cho)明顯升高,N-乙酰天門鼕氨痠(NAA)明顯降低,Cho/NAA 比值為5.13±4.72(1.46~15.26),5例齣現乳痠峰增高。DWI 示1例實性病例可見明顯擴散受限,其餘7例囊實性病例均未見明顯擴散受限,其平均相對 ADC 值為1.60±0.58。結論 PA 符閤低級彆膠質瘤的絕大多數影像學錶現,但其 MRI 生理代謝成像有一定的特徵性,其灌註明顯高于同級彆的膠質瘤,正確認識其錶現有助于提高診斷和鑒彆診斷的準確性。
목적탐토모세포형성형세포류(PA)적자공진관주성상(PWI)、확산가권성상(DWI)、자공진파보성상(MRS)화자민감가권성상(SWI)적영상학특점,제고대본병적진단준학성。자료여방법회고성분석11례경수술병리증실적 PA 적MRI 표현,분석기상규 MRI 급생리대사성상특점。결과완전위낭성혹실성병변각1례,기여9례위낭실성병변;10례병변표현위혼잡장 T1장 T2신호,FLAIR 정혼잡고신호;1례표현위균균장 T1장 T2신호,FLAIR 정고신호;증강소묘병변실성부분화낭벽급벽결절균정명현강화,6례위화상양강화,3례위결절상화화배상강화,1례위명현강화,1례위경도배형강화;3례 SWI 표현위편상저신호,2례위점상저신호,2례미견저신호현시,기평균종류내저신호분급위1.57급。PWI 표현위고관주,기최대상대뇌혈용량위2.64±1.22。종류실성부분담감(Cho)명현승고,N-을선천문동안산(NAA)명현강저,Cho/NAA 비치위5.13±4.72(1.46~15.26),5례출현유산봉증고。DWI 시1례실성병례가견명현확산수한,기여7례낭실성병례균미견명현확산수한,기평균상대 ADC 치위1.60±0.58。결론 PA 부합저급별효질류적절대다수영상학표현,단기 MRI 생리대사성상유일정적특정성,기관주명현고우동급별적효질류,정학인식기표현유조우제고진단화감별진단적준학성。
Purpose To investigate the imaging characteristics and accuracy of diagnosing pilocytic astrocytoma (PA) with perfusion weighted imaging (PWI), diffusion weighted imaging (DWI), magnetic resonance sprectroscopy, susceptibility weighted imaging (SWI) and diffusion tensor imaging. Material and Methods MRI imaging of 11 patients with PA was retrospectively analyzed for functional imaging features. Results In 11 patients with PA, there were 9 mixed cystic and solid lesions, 1 case of cystic lesion and 1 case with solid lesion. Ten lesions showed mixed hypointensity on T1WI, and mixed hyperintensity on T2WI and FLAIR. One case was hypointense on T1WI, and hyperintense on T2WI and FLAIR. Prominent contrast enhancement was seen in the solid portion, capsular wall and mural nodules. On SWI 3 cases showed patchy low signal, 2 cases of dot-like low signal and 2 cases without low signal, with average intratumoral susceptibility signal intensity classification of 1.57. PWI findings were characterized by high perfusion with relative cerebral blood volume averaging 2.64±1.22. There was elevated choline component in the solid portion with significantly decreased NAA with average Cho/NAA ratio of 5.13±4.72 (1.46-15.26). Lactate peak was increased in 5 cases. On DWI there was limited diffusion in 1 case. 7 cases did not demonstrate limited diffusion with average relative apparent diffusion coefficient of 1.60±0.58. Conclusion Most MRI features of pilocystic astrocytoma are consistent with low grade glioma. There are characteristic functional imaging findings with higher perfusion than other gliomas. Functional MRI can evaluate tumor metabolism and prognosis.