CAJ | 학술논문

目的：评价总胆汁酸（TBA）、癌胚抗原（CEA）、糖类抗原19‐9（CA199）、糖类抗原72‐4（CA72‐4）联合检测在胃癌中的诊断价值。方法采用该院2013年1月到2014年4月的住院胃癌各期患者共53例，胃良性病变组80例和健康对照组120例，分别对其血清进行总胆汁酸（TBA）、CEA、CA199、CA72‐4浓度检测。结果胃癌组的检测指标依次为TBA （59．55±20．56）μmmol／L、CEA（17．26±11．69）g／L、CA199（82．08±6．9）U／mL、CA72‐4（68．65±23．05）U／mL ，均高于其他两组，差异具有统计学意义（P＜0．05）。胃良性病变组与健康对照组CEA、CA199、CA72‐4浓度比较差异无统计学意义（P＞0．05）。结论 TBA、CEA、CA199、CA72‐4指标可作为临床判断胃肿瘤的检测指标，指标的联合检测对胃癌的临床判断疗效和预后具有较高的临床价值。
목적：평개총담즙산（TBA）、암배항원（CEA）、당류항원19‐9（CA199）、당류항원72‐4（CA72‐4）연합검측재위암중적진단개치。방법채용해원2013년1월도2014년4월적주원위암각기환자공53례，위량성병변조80례화건강대조조120례，분별대기혈청진행총담즙산（TBA）、CEA、CA199、CA72‐4농도검측。결과위암조적검측지표의차위TBA （59．55±20．56）μmmol／L、CEA（17．26±11．69）g／L、CA199（82．08±6．9）U／mL、CA72‐4（68．65±23．05）U／mL ，균고우기타량조，차이구유통계학의의（P＜0．05）。위량성병변조여건강대조조CEA、CA199、CA72‐4농도비교차이무통계학의의（P＞0．05）。결론 TBA、CEA、CA199、CA72‐4지표가작위림상판단위종류적검측지표，지표적연합검측대위암적림상판단료효화예후구유교고적림상개치。
Objective To evaluate the value of diagnosis of total bile acid (TBA ) ,CEA ,CA199 ,CA72‐4 in gastric carcinoma combined detection .Methods From 2013 January to 2014 April in hospital of each stage of gastric cancer in 53 patients ,80 patients in benign gastric disease group and healthy group of 120 people ,were detected the concentration of TBA ,CEA ,CA199 respectively , the serum CA72‐4 .Results Three testing groups ,detecting indexes in patients with gastric cancer group were TBA (59 .55 ± 20 . 56)μmmol/L ,CEA (17 .26 ± 11 .69)g/L ,CA199 (82 .08 ± 6 .9)U/mL ,CA72‐4 (68 .65 ± 23 .05)U/mL ,concentrations were higher than the other two groups ,with statistically significant difference between groups (P< 0 .05) .No statistical significance of CEA , CA199 ,CA72‐4 between group differences in gastric benign disease group and the healthy control group (P>0 .05) .Conclusion TBA ,CEA ,CA199 ,CA72‐4 index can be used as the detection index of clinical judgment of gastric tumor ,with a high clinical value of combined detection indexes of gastric cancer clinical treatment and prognosis .