中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
14期
67-70
,共4页
莫罗匹星%中心静脉导管%血液透析%感染
莫囉匹星%中心靜脈導管%血液透析%感染
막라필성%중심정맥도관%혈액투석%감염
Mupirocin%Central venous catheterization%Hemodialysis%Infection
目的：探讨莫匹罗星对血透患者中心静脉置管感染的预防及治疗作用。方法选取114例2013年7月~2014年7月期间来我院就诊并使用中心静脉导管治疗的血透患者，将所有患者分为两组。观察组57例，患者在血透治疗后，在常规换药后于中心静脉导管的出管口外用莫匹罗星治疗。对照组57例，使用常规换药方法治疗。对比两组患者的痊愈时间、感染发生率和治疗总有效率。结果观察组颈内静脉感染2例，感染率为3.5%，置管时间（22.42±5.22）d，股静脉感染3例，感染率5.3%，置管时间（19.16±3.13）d，锁骨下静脉感染2例，感染率3.5%，置管时间（29.23±4.92）d；对照组静脉感染6例，感染率为10.5%，置管时间（16.82±4.33）d，股静脉感染4例，感染率为7.0%，置管时间（15.26±3.88）d，锁骨下静脉感染4例，感染率7.0%，置管时间（19.65±4.68）d，差异有统计学意义（P<0.05）。结论静脉置管的导管口处外涂莫匹罗星能有效地降低中心静脉导管相关感染率，使患者的导管留置时间延长，患者易于接受，且费用较低，操作简便，值得推广。
目的：探討莫匹囉星對血透患者中心靜脈置管感染的預防及治療作用。方法選取114例2013年7月~2014年7月期間來我院就診併使用中心靜脈導管治療的血透患者，將所有患者分為兩組。觀察組57例，患者在血透治療後，在常規換藥後于中心靜脈導管的齣管口外用莫匹囉星治療。對照組57例，使用常規換藥方法治療。對比兩組患者的痊愈時間、感染髮生率和治療總有效率。結果觀察組頸內靜脈感染2例，感染率為3.5%，置管時間（22.42±5.22）d，股靜脈感染3例，感染率5.3%，置管時間（19.16±3.13）d，鎖骨下靜脈感染2例，感染率3.5%，置管時間（29.23±4.92）d；對照組靜脈感染6例，感染率為10.5%，置管時間（16.82±4.33）d，股靜脈感染4例，感染率為7.0%，置管時間（15.26±3.88）d，鎖骨下靜脈感染4例，感染率7.0%，置管時間（19.65±4.68）d，差異有統計學意義（P<0.05）。結論靜脈置管的導管口處外塗莫匹囉星能有效地降低中心靜脈導管相關感染率，使患者的導管留置時間延長，患者易于接受，且費用較低，操作簡便，值得推廣。
목적：탐토막필라성대혈투환자중심정맥치관감염적예방급치료작용。방법선취114례2013년7월~2014년7월기간래아원취진병사용중심정맥도관치료적혈투환자，장소유환자분위량조。관찰조57례，환자재혈투치료후，재상규환약후우중심정맥도관적출관구외용막필라성치료。대조조57례，사용상규환약방법치료。대비량조환자적전유시간、감염발생솔화치료총유효솔。결과관찰조경내정맥감염2례，감염솔위3.5%，치관시간（22.42±5.22）d，고정맥감염3례，감염솔5.3%，치관시간（19.16±3.13）d，쇄골하정맥감염2례，감염솔3.5%，치관시간（29.23±4.92）d；대조조정맥감염6례，감염솔위10.5%，치관시간（16.82±4.33）d，고정맥감염4례，감염솔위7.0%，치관시간（15.26±3.88）d，쇄골하정맥감염4례，감염솔7.0%，치관시간（19.65±4.68）d，차이유통계학의의（P<0.05）。결론정맥치관적도관구처외도막필라성능유효지강저중심정맥도관상관감염솔，사환자적도관류치시간연장，환자역우접수，차비용교저，조작간편，치득추엄。
Objective To analyze and discuss the prevention and treatment effect of mupirocin on infection for hemodialysis patients with central venous catheterization (CVC). Methods A total of 114 cases hemodialysis patients receiving CVC in our hospital from July 2013 to July 2014 were randomly divided into two groups. 57 patients in the observation group were given externally mupirocin at the outlet of central venous catheter in addition to conventional medicine. 57 cases in the control group were given only conventional medicine. Healing time, incidence of infection and the total treatment efficiency of the two groups were compared. Results In the observation group, there were 2 cases of internal jugular vein infection with an infection rate of 3.5% and the average catheterization time was (22.42±5.22)d. And there were a total of 3 cases of femoral vein infection with an infection rate of 5.3% and the catheterization time was (19.16±3.13)d. Also there were 2 cases of subclavian vein infection with an infection rate of 3.5%and the catheter-ization time was (29.23±4.92)d;In the control group, there were a total of 6 cases of intravenous infection with an infec-tion rate of 10.5% and the catheterization time was (16.82±4.33)d. And there were 4 cases of femoral vein infection with an infection rate of 7.0% and the catheterization time was (15.26±3.88)d. Also there were 4 cases of subclavian vein infection with an infection rate of 7.0% and the catheterization time was (19.65±4.68)d. There were significant dif-ferences in the treatment outcomes between the two groups (P<0.05). Conclusion Mupirocin application at the outlet of central venous catheter effectively reduces central venous catheter-related infections and increases patient's catheters indwelling time. It is easy for patients to accept, relative cheap and easy to operate, thus its use is worth promoting.
