心脑血管病防治
心腦血管病防治
심뇌혈관병방치
PREVENTION AND TREATMENT OF CARDIO-CEREBRAL-VASCULAR DISEASE
2015年
3期
188-190
,共3页
朱洁莹%李琴%韩丽英%刘吉祥%马宝红%杨梅霞%王素兰%常超%信栓力
硃潔瑩%李琴%韓麗英%劉吉祥%馬寶紅%楊梅霞%王素蘭%常超%信栓力
주길형%리금%한려영%류길상%마보홍%양매하%왕소란%상초%신전력
同型半胱氨酸%高敏C反应蛋白%冠脉粥样硬化
同型半胱氨痠%高敏C反應蛋白%冠脈粥樣硬化
동형반광안산%고민C반응단백%관맥죽양경화
Homocysteine%High_sensitivity C_reactive protein%Coronary atherosclerosis
目的：探讨同型半胱氨酸（Hcy ）和超敏C反应蛋白（hsCRP ）联合检测诊断冠心病（coronary heart disease ， CHD ）的临床意义。方法220例疑似CHD患者按照冠状动脉造影结果分为CHD组患者143例和非CHD组患者77例，测量并分析两组患者Hcy和hsCRP水平。结果 CHD患者的Hcy和hsCRP明显高于非CHD组，差异有统计学意义（ P＜0.05），多因素Logistic回归分析显示Hcy、hsCRP均为CHD的危险因素，两指标联合检测显示与CHD呈强相关（OR＝14.32，P＜0.01），对CHD的诊断准确性为94.09％，Kappa值为0.87（ P＝1.0）。结论 Hcy联合hsCRP诊断CHD可能有较大的临床意义。
目的：探討同型半胱氨痠（Hcy ）和超敏C反應蛋白（hsCRP ）聯閤檢測診斷冠心病（coronary heart disease ， CHD ）的臨床意義。方法220例疑似CHD患者按照冠狀動脈造影結果分為CHD組患者143例和非CHD組患者77例，測量併分析兩組患者Hcy和hsCRP水平。結果 CHD患者的Hcy和hsCRP明顯高于非CHD組，差異有統計學意義（ P＜0.05），多因素Logistic迴歸分析顯示Hcy、hsCRP均為CHD的危險因素，兩指標聯閤檢測顯示與CHD呈彊相關（OR＝14.32，P＜0.01），對CHD的診斷準確性為94.09％，Kappa值為0.87（ P＝1.0）。結論 Hcy聯閤hsCRP診斷CHD可能有較大的臨床意義。
목적：탐토동형반광안산（Hcy ）화초민C반응단백（hsCRP ）연합검측진단관심병（coronary heart disease ， CHD ）적림상의의。방법220례의사CHD환자안조관상동맥조영결과분위CHD조환자143례화비CHD조환자77례，측량병분석량조환자Hcy화hsCRP수평。결과 CHD환자적Hcy화hsCRP명현고우비CHD조，차이유통계학의의（ P＜0.05），다인소Logistic회귀분석현시Hcy、hsCRP균위CHD적위험인소，량지표연합검측현시여CHD정강상관（OR＝14.32，P＜0.01），대CHD적진단준학성위94.09％，Kappa치위0.87（ P＝1.0）。결론 Hcy연합hsCRP진단CHD가능유교대적림상의의。
Objective To investigate the clinical significance of homocysteine (Hcy) and high_sensitivity C_reactive protein (hsCRP) on diagnosis of coronary heart disease (CHD).Methods 220 patients who suspected with CHD were divided into CHD group (n=143) and non_CHD group (n=77) by coronary angiography. Hcy and HsCRP standard were measured and analysed. Results Hcy and hsCRP in patients diagnosed with CHD were significantly higher than those of non_CHD group ,significance of CHD diagnosis in Hcy and HsCRP was judged ( P<0.05).Hcy and hsCRP were risk factors for CHD by multivariate logistic regression analysis ,two indexes joint detection showed that there’s strong correlation between CHD and joint detection results (OR=14.32 , P<0.001 ).Diagnostic accuracy was 94.09% and Kappa was 0.87 ( P=1.0 ). Conclusions Hcy combined with hsCRP may have significantly clinical significance on CHD diagnose .
