CAJ | 학술논문

目的：探讨3D FSE 的 pc-ASL 技术对桥小脑角区肿瘤术后复发的诊断价值。方法：选取21例桥小脑角区占位性病变术后患者，行常规平扫及增强序列，在增强前扫描 pc-ASL 序列。将 pc-ASL 功能图像与增强后 Ax 3D T1 WI 融合，测量异常强化区域及对侧正常脑组织的 CBF 值，评价是否存在肿瘤复发。结果：全部21例手术区出现异常强化区患者，13例为复发。17例患者行 DSC-PWI 失败，图像无法满足诊断需求。全部21例 pc-ASL 检查成功。肿瘤复发区域的CBF 值为（64．2±3．03）mL／100g／min，对侧正常脑实质的 CBF 值为（52．5±1．89）mL／100g／min。肿瘤复发区域的 CBF值明显高于对照侧脑组织，两者之间差异有统计学意义（t＝12．498，P ＜0．05）。结论：基于3D FSE 的 pc-ASL 序列安全无创，无需注射对比剂，磁敏感效应影响小，可以用于评估桥小脑角区肿瘤有无术后复发。
목적：탐토3D FSE 적 pc-ASL 기술대교소뇌각구종류술후복발적진단개치。방법：선취21례교소뇌각구점위성병변술후환자，행상규평소급증강서렬，재증강전소묘 pc-ASL 서렬。장 pc-ASL 공능도상여증강후 Ax 3D T1 WI 융합，측량이상강화구역급대측정상뇌조직적 CBF 치，평개시부존재종류복발。결과：전부21례수술구출현이상강화구환자，13례위복발。17례환자행 DSC-PWI 실패，도상무법만족진단수구。전부21례 pc-ASL 검사성공。종류복발구역적CBF 치위（64．2±3．03）mL／100g／min，대측정상뇌실질적 CBF 치위（52．5±1．89）mL／100g／min。종류복발구역적 CBF치명현고우대조측뇌조직，량자지간차이유통계학의의（t＝12．498，P ＜0．05）。결론：기우3D FSE 적 pc-ASL 서렬안전무창，무수주사대비제，자민감효응영향소，가이용우평고교소뇌각구종류유무술후복발。
Objective:The purpose of this study was to assess the diagnostic value of 3D FSE pseudo-continuous arte-rial spin labeling (pCASL)technique in evaluating post-operative recurrence of cerebellopontine angle tumor.Methods:21 post-operative patients with cerebellopontine angle tumor underwent pre-and post-contrast MRI scans.Perfusion-weighted MR imaging (PWI)with pCASL technique was performed before contrast injection.The CBF maps generated from pCASL were fused with post-contrast 3D T1 WI.The CBF values of abnormal enhanced area and contralateral normal brain tissue were measured and statistically analyzed to assess whether there was a recurrence of the neoplasm.Results:The neoplasm recurrence was found in 13/21 cases.DSC-PWI failed to generate functional maps in 17/21 cases due to the susceptibility ar-tifact;however,all 21 cases successfully underwent pCASL scan using 3D-FSE sequence.The mean CBF values were (64.2 ±3.03)mL/100g/min for the recurrent neoplasm and (52.5 ±1.89)mL/100g/min for the contralateral normal brain tis-sue,respectively.There was statistically significant difference (t=12.498,P <0.05).Conclusion:With several advantages, including non-invasive,non-contrast and free of susceptibility effect,3D pCASL technique can be used to assess the tumor recurrence in cerebellopontine angle.