中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
15期
108-111
,共4页
地佐辛%痛觉过敏%芬太尼%瑞芬太尼%七氟醚
地佐辛%痛覺過敏%芬太尼%瑞芬太尼%七氟醚
지좌신%통각과민%분태니%서분태니%칠불미
Dezocine%Hyperpathia%Fentanyl%Remifentanil%Sevoflurane
目的：研究地佐辛对瑞芬太尼复合七氟醚麻醉致痛觉过敏的预防效果。方法将我院收治的84例上腹部手术患者作为观察对象，两组患者均采用瑞芬太尼复合七氟醚麻醉，观察组患者于手术结束前20 min给予地佐辛，对照组患者于手术结束前给予芬太尼，利用疼痛六点行为评分法（BRS6）及VAS评分法对患者手术前后疼痛程度进行评分，并统计两组患者的苏醒时间、拔管时间和离开PACU时间及麻醉不良反应。结果两组术前BRS6及VAS评分相比，差异无统计学意义（P>0.05），手术后1 h，观察组BRS6及VAS评分明显低于对照组；观察组苏醒时间、拔管时间和离开PACU时间分别为（28.96±5.54）min、（21.08±7.45）min和（58.05±10.32）min，对照组为（38.62±5.05）min、（57.08±5.36）min和（69.05±9.52）min，两组相比，差异有统计学意义（P<0.05）；观察组麻醉后1 d内呕吐发生率明显低于对照组（P<0.05）。结论地佐辛能显著抑制瑞芬太尼复合七氟醚麻醉致患者痛觉过敏，值得推广借鉴。
目的：研究地佐辛對瑞芬太尼複閤七氟醚痳醉緻痛覺過敏的預防效果。方法將我院收治的84例上腹部手術患者作為觀察對象，兩組患者均採用瑞芬太尼複閤七氟醚痳醉，觀察組患者于手術結束前20 min給予地佐辛，對照組患者于手術結束前給予芬太尼，利用疼痛六點行為評分法（BRS6）及VAS評分法對患者手術前後疼痛程度進行評分，併統計兩組患者的囌醒時間、拔管時間和離開PACU時間及痳醉不良反應。結果兩組術前BRS6及VAS評分相比，差異無統計學意義（P>0.05），手術後1 h，觀察組BRS6及VAS評分明顯低于對照組；觀察組囌醒時間、拔管時間和離開PACU時間分彆為（28.96±5.54）min、（21.08±7.45）min和（58.05±10.32）min，對照組為（38.62±5.05）min、（57.08±5.36）min和（69.05±9.52）min，兩組相比，差異有統計學意義（P<0.05）；觀察組痳醉後1 d內嘔吐髮生率明顯低于對照組（P<0.05）。結論地佐辛能顯著抑製瑞芬太尼複閤七氟醚痳醉緻患者痛覺過敏，值得推廣藉鑒。
목적：연구지좌신대서분태니복합칠불미마취치통각과민적예방효과。방법장아원수치적84례상복부수술환자작위관찰대상，량조환자균채용서분태니복합칠불미마취，관찰조환자우수술결속전20 min급여지좌신，대조조환자우수술결속전급여분태니，이용동통륙점행위평분법（BRS6）급VAS평분법대환자수술전후동통정도진행평분，병통계량조환자적소성시간、발관시간화리개PACU시간급마취불량반응。결과량조술전BRS6급VAS평분상비，차이무통계학의의（P>0.05），수술후1 h，관찰조BRS6급VAS평분명현저우대조조；관찰조소성시간、발관시간화리개PACU시간분별위（28.96±5.54）min、（21.08±7.45）min화（58.05±10.32）min，대조조위（38.62±5.05）min、（57.08±5.36）min화（69.05±9.52）min，량조상비，차이유통계학의의（P<0.05）；관찰조마취후1 d내구토발생솔명현저우대조조（P<0.05）。결론지좌신능현저억제서분태니복합칠불미마취치환자통각과민，치득추엄차감。
Objective To investigate the preventive effect research of dezocine in the treatment of hyperpathia caused by remifentanil and sevoflurane. Methods A total of 84 epigastric operation patients were collected into this study. Both of them were anesthetized by the therapy of remifentanil and sevoflurane. Patients of observation group were treated with dezocine before the end of the operation. Patients in control group were treated with fentanyl before the end of the operation. The six behavioral pain score (BRS6) and VAS score were used to evaluate the degree of pain in patients before and after surgery, and recovery time, extubation time and leave PACU time as well as anesthesia ad-verse reactions in the two groups were recorded. Results The differences of preoperative BRS6 and VAS score were not statistically significant (P>0.05), BRS6 and VAS scores at 1 h after surgery in the observation group were significantly lower than the control group; recovery time, extubation time and leave PACU time in observation group were (28.96±5.54) min, (21.08±7.45) min and (58.05±10.32) min, while (38.62±5.05) min, (57.08±5.36) min and (69.05±9.52) min in the control group, the differences were statistically significant (P<0.05); 1d after anesthesia, incidence of vomiting in the observation group was significantly lower than the control group (P<0.05). Conclusion Dezocine has perfect preven-tive effect in the treatment of hyperpathia caused by remifentanil and sevoflurane.
