CAJ | 학술논문

目的：探究中、重度慢性牙周炎与原发性高血压之间的相关性。方法：选取我院近年来（2010年12月～2013年1月）体检的健康人群35例（A组），同期收治中、重度慢性牙周炎患者32例（B组），慢性牙周炎伴原发性高血压患者37例（C组）为研究对象。对3组对象的菌斑指数、探诊深度、附着丧失、出血指数、抗心磷脂抗体IgG等指标进行比较研究。结果：①3组对象的各项牙周指标比较差异明显，C组指标高于A、B组，B组指标高于A组（ P均＜0．05）；②3组对象的抗心磷脂抗体IgG指标比较差异明显，C组指标高于A、B组，B组指标高于A组（P均＜0．05）；③3组对象的抗心磷脂抗体IgG指标与菌斑指数、探诊深度、附着丧失、出血指数之间正显著相关。结论：原发性高血压可加重慢性牙周炎患者病情，同时慢性牙周炎可导致患者抗心磷脂抗体升高，增加患者动脉粥样硬化的发生风险，二者相互作用相互影响。
목적：탐구중、중도만성아주염여원발성고혈압지간적상관성。방법：선취아원근년래（2010년12월～2013년1월）체검적건강인군35례（A조），동기수치중、중도만성아주염환자32례（B조），만성아주염반원발성고혈압환자37례（C조）위연구대상。대3조대상적균반지수、탐진심도、부착상실、출혈지수、항심린지항체IgG등지표진행비교연구。결과：①3조대상적각항아주지표비교차이명현，C조지표고우A、B조，B조지표고우A조（ P균＜0．05）；②3조대상적항심린지항체IgG지표비교차이명현，C조지표고우A、B조，B조지표고우A조（P균＜0．05）；③3조대상적항심린지항체IgG지표여균반지수、탐진심도、부착상실、출혈지수지간정현저상관。결론：원발성고혈압가가중만성아주염환자병정，동시만성아주염가도치환자항심린지항체승고，증가환자동맥죽양경화적발생풍험，이자상호작용상호영향。
Objective:To investigate the association of moderate-severe chronic periodontitis with essential hypertension.Methods: Included in this study were 35 healthy subjects undergone physical examination between December 2010 and January 2013(group A),32 patients with moderate or severe chron-ic periodontitis received treatment in the corresponding period(group B) and 37 patients with chronic periodontitis associated with essential hypertension (group C).The clinical data were compared regarding the plaque index,probing depth,attachment loss,gingival bleeding index and anticardiolipin anti-body IgG level among the three groups.Results:Group C had the highest periodontal indexes and anticardiolipin antibody IgG level ,and the indexes were lowest for group A(all P<0.05).The anticardiolipin antibody IgG level was positively correlated with the plaque index,probing depth,attachment loss, gingival bleeding index in the three groups.Conclusion:Essential hypertension can aggravate the condition of patients with chronic periodontitis that may lead to elevated level of anticardiolipin antibody and increased risks of atherosclerosis in such patients .