CAJ | 학술논문

目的：为了进一步探讨和研究比较同期放化方法在治疗口腔癌实践过程中的临床实际治疗效果，从而为相关的临床研究提供借鉴依据。方法：本文选取了我院2007年1月～2011年1月期间收治的口腔癌患者147例为研究对象，随机将患者分成2组，分别为同期放化组（78例采用同期放化疗治疗方法）和序贯放化组（69例采用序贯放化疗治疗方法）。观察比较2组患者实施不同临床治疗方法后的临床治疗效果和1年、2年、3年生存情况。结果：（1）治疗总有效率组间比较，同期放化组患者显著的高于序贯放化组，且差异具有统计学意义（x2＝9．0683，P＝0．0026）；（2）患者实施治疗后1年、2年、3年生存率组间比较，同期放化组患者均显著的高于序贯放化组，且差异具有统计学意义（ P均＜0．05）。结论：在临床针对口腔癌患者实施治疗的实践过程中，采用同期放化治疗方法较采用序贯放化治疗方法的临床治疗效果显著，是临床治疗口腔癌的理想可靠选择。
목적：위료진일보탐토화연구비교동기방화방법재치료구강암실천과정중적림상실제치료효과，종이위상관적림상연구제공차감의거。방법：본문선취료아원2007년1월～2011년1월기간수치적구강암환자147례위연구대상，수궤장환자분성2조，분별위동기방화조（78례채용동기방화료치료방법）화서관방화조（69례채용서관방화료치료방법）。관찰비교2조환자실시불동림상치료방법후적림상치료효과화1년、2년、3년생존정황。결과：（1）치료총유효솔조간비교，동기방화조환자현저적고우서관방화조，차차이구유통계학의의（x2＝9．0683，P＝0．0026）；（2）환자실시치료후1년、2년、3년생존솔조간비교，동기방화조환자균현저적고우서관방화조，차차이구유통계학의의（ P균＜0．05）。결론：재림상침대구강암환자실시치료적실천과정중，채용동기방화치료방법교채용서관방화치료방법적림상치료효과현저，시림상치료구강암적이상가고선택。
Abstact Objective:To investigate the actual effect of concurrent chemoradiotherapy for oral cancer and then provide relevant refer-ence for clinical research.Methods:147 patients with oral cancer between 2007 January and 2011 January were randomly divided into two groups:Concurrent chemoradiotherapy group (78 cases with concurrent chemotherapy treatment) and sequential chemoradiotherapy group (69 cases with sequential chemotherapy treatment) .The therapeutic effect and 1-year, 2-year, 3-year survival rate in the two groups was compared.Results:The overall response rate of concurrent chemoradiotherapy group was significantly higher than that of the sequential chemoradiotherapy group (χ2=9.0683.P=0.0026).Concurrent chemoradiotherapy group has better outcomes than the se-quential chemoradiotherapy group for the 1-year, 2-year and 3-year survival rate (P <0.05).Conclusion:Concurrent chemoradio-therapy could improve the near and future effect of patients with oral cancer, which may be the ideal and reliable selection for these pa-tients.