CAJ | 학술논문

目的：探讨剖宫产手术中应用米索前列醇和催产素控制产后出血的效果。方法：选取2013年6月～2014年6月我院妇产科收治的行剖宫产手术的产妇180例，将其随机分为观察1组、观察2组与观察3组，每组患者60例。观察1组患者单用米索前列醇，观察2组患者单用催产素，观察3组患者采用米索前列醇与催产素联合用药。观察并比较三组患者术中、术后2h 及术后24h 的出血量。结果：观察3组患者的产后出血率为1.67%，较观察1组患者产后出血率5.0%与观察2组患者产后出血率8.33%明显降低，差异较为显著，均具有统计学意义；观察1组与观察2组患者产后出血率比较，两组间差异具有统计学意义；在出血量方面，观察3组患者术中、术后2h 及术后24h 的出血量较观察1组与观察2组患者出血量明显降低，差异均具有统计学意义；观察1组与观察2组患者手术中出血量间比较差异无无统计学意义，但是在产后2h 与产后24h，观察1组出血量明显低于观察2组，两组间差异具有统计学意义。结论：在剖宫产手术中联合应用米索前列醇与催产素能够有效的控制产后出血量，具有良好的临床疗效，值得在临床上进一步的推广与应用。
목적：탐토부궁산수술중응용미색전렬순화최산소공제산후출혈적효과。방법：선취2013년6월～2014년6월아원부산과수치적행부궁산수술적산부180례，장기수궤분위관찰1조、관찰2조여관찰3조，매조환자60례。관찰1조환자단용미색전렬순，관찰2조환자단용최산소，관찰3조환자채용미색전렬순여최산소연합용약。관찰병비교삼조환자술중、술후2h 급술후24h 적출혈량。결과：관찰3조환자적산후출혈솔위1.67%，교관찰1조환자산후출혈솔5.0%여관찰2조환자산후출혈솔8.33%명현강저，차이교위현저，균구유통계학의의；관찰1조여관찰2조환자산후출혈솔비교，량조간차이구유통계학의의；재출혈량방면，관찰3조환자술중、술후2h 급술후24h 적출혈량교관찰1조여관찰2조환자출혈량명현강저，차이균구유통계학의의；관찰1조여관찰2조환자수술중출혈량간비교차이무무통계학의의，단시재산후2h 여산후24h，관찰1조출혈량명현저우관찰2조，량조간차이구유통계학의의。결론：재부궁산수술중연합응용미색전렬순여최산소능구유효적공제산후출혈량，구유량호적림상료효，치득재림상상진일보적추엄여응용。
Objective To explore effect of using misoprostol and oxytocin to control postpartum hemorrhage in the opera-tion of cesarean delivery. Methods There are 180 cases of maternal come to our hospital for the operation of cesarean delivery at the time from June 2013 to June 2014, and then devided them into observation group 1, observe group 2 and observation group 3 with 60 maternals in each group randomly. The observation group 1 was given misoprostol for treatment, the observa-tion group 2 was given postpartum hemorrhage for treatment independently, and the observation group 3 was given misoprostol combine with postpartum hemorrhage for treatment. Observed and compared the amout of bleeding of the three groups at thetime of in the process of operation, 2 hours after the operation and 24 hours after the operation. Results The bleeding rate after childbirth of observation group 3 is 1.67 %, we can find it is obvious lower than 5.0 % of the observation group 1 and 8.33 % of the observation group 2, the difference between them have statistically significant; the difference between observation group 1 with observation group 2 have statistically significant; In the amout of bleeding, we can find out that the three groups at the time of in the process of operation, 2 hours after the operation and 24 hours after the operation, observation group 3 is obvious lower than group 1 and 2, the difference between them have statistically significant; But at the time of in the process of operation, the difference between observation group 1 with observation group 2 have no statistically significant; But at the time of 2 hours after the operation and 24 hours after the operation, the difference between observation group 1 with observation group 2 have nsta-tistically significant. Conclusion Using misoprostol combine with oxytocin to control postpartum hemorrhage in the operation of cesarean delivery, have very good clnical effect, it was worth to be fruther promoted and applied in clinic.