CAJ | 학술논문

目的：分析2型糖尿病患者夜间低血糖的发生情况，探讨胰岛素减量降低夜间低血糖风险的可行性。方法：120例住院2型糖尿病患者列入调查，比较调整剂量并加用阿卡波糖组（观察组）与单用胰岛素不加用阿卡波糖组（对照组）的血糖水平；观察组患者应用调整方案治疗10d，对比调整方案前、后的夜间低血糖发生情况。结果：观察组患者的夜间血糖平均值显著低于对照组；观察组患者调整胰岛素治疗方案之后的夜间低血糖发生率低于调整前。结论：住院2型糖尿病患者检测夜间血糖水平有助于预测夜间低血糖的发生，胰岛素适当减量联合阿卡波糖口服有助于降低夜间低血糖的风险，值得临床进一步研究。
목적：분석2형당뇨병환자야간저혈당적발생정황，탐토이도소감량강저야간저혈당풍험적가행성。방법：120례주원2형당뇨병환자렬입조사，비교조정제량병가용아잡파당조（관찰조）여단용이도소불가용아잡파당조（대조조）적혈당수평；관찰조환자응용조정방안치료10d，대비조정방안전、후적야간저혈당발생정황。결과：관찰조환자적야간혈당평균치현저저우대조조；관찰조환자조정이도소치료방안지후적야간저혈당발생솔저우조정전。결론：주원2형당뇨병환자검측야간혈당수평유조우예측야간저혈당적발생，이도소괄당감량연합아잡파당구복유조우강저야간저혈당적풍험，치득림상진일보연구。
Objective To analyze the relationship between the occurrence of nocturnal hypoglycemia and quantitative indi-cators in patient with type 2 diabetes. And explore the feasibility of reducing risk of nocturnal hypoglycemia by reducing insulin dose. Method: 120 hospitalized patients with type 2 diabetes were included in the survey. The quantitative indicators of the ob-servation group and the control group were compared then. The observation group took insulin adjustment program for 10 days. Then compare the occurrence of nocturnal hypoglycemia before and after the treatment. Results The mean nighttime blood glucose of the observation group was significantly lower than that of the control group. After the treatment of insulin dose adjust-ment, the incidence of nocturnal hypoglycemia in the observation group was lower than before. Conclusion: Detect nighttime glucose levels may predict the occurrence of nocturnal hypoglycemia of hospitalized patients with type 2 diabetes. Appropriate reduction of insulin combined with acarbose helps reduce risk of nocturnal hypoglycemia.