医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
11期
2090-2092
,共3页
急性心肌梗死%老年%尿酸
急性心肌梗死%老年%尿痠
급성심기경사%노년%뇨산
Acute myocardial infarction%Elderly%Uric acid
目的:探讨老年急性心肌梗死患者血尿酸水平变化对患者预后的影响。方法对2012年12月至2013年11月内蒙古医科大学附属医院收治的110例老年急性心肌梗死患者行血尿酸测定,男性以尿酸水平>420μmol/L,女性以尿酸水平>357μmol/L定义为高尿酸血症,根据患者是否患有高尿酸血症分为高尿酸血症组( A组,24例)和正常血尿酸组( B组,86例)。比较分析两组间实验室及超声检查、冠状动脉病变及预后。结果①A 组三酰甘油水平及左心房内径显著高于 B 组[(1.74±1.04) mmol/L比(1.08±0.54) mmol/L,(42±5) mm 比(39±6) mm,P <0.05或 P <0.01],而A组左心室射血分数显著低于B组[(46±14)%比(52±10)%,P<0.05]。②A组患者一级终点及二级终点事件的发生率均显著高于B组[24.0%(6例)比9.2%(8例),64.0%(16例)比35.6%(31例),P<0.05]。结论抑制尿酸水平的升高对于改善老年急性心肌梗死患者的预后可能具有重要意义。
目的:探討老年急性心肌梗死患者血尿痠水平變化對患者預後的影響。方法對2012年12月至2013年11月內矇古醫科大學附屬醫院收治的110例老年急性心肌梗死患者行血尿痠測定,男性以尿痠水平>420μmol/L,女性以尿痠水平>357μmol/L定義為高尿痠血癥,根據患者是否患有高尿痠血癥分為高尿痠血癥組( A組,24例)和正常血尿痠組( B組,86例)。比較分析兩組間實驗室及超聲檢查、冠狀動脈病變及預後。結果①A 組三酰甘油水平及左心房內徑顯著高于 B 組[(1.74±1.04) mmol/L比(1.08±0.54) mmol/L,(42±5) mm 比(39±6) mm,P <0.05或 P <0.01],而A組左心室射血分數顯著低于B組[(46±14)%比(52±10)%,P<0.05]。②A組患者一級終點及二級終點事件的髮生率均顯著高于B組[24.0%(6例)比9.2%(8例),64.0%(16例)比35.6%(31例),P<0.05]。結論抑製尿痠水平的升高對于改善老年急性心肌梗死患者的預後可能具有重要意義。
목적:탐토노년급성심기경사환자혈뇨산수평변화대환자예후적영향。방법대2012년12월지2013년11월내몽고의과대학부속의원수치적110례노년급성심기경사환자행혈뇨산측정,남성이뇨산수평>420μmol/L,녀성이뇨산수평>357μmol/L정의위고뇨산혈증,근거환자시부환유고뇨산혈증분위고뇨산혈증조( A조,24례)화정상혈뇨산조( B조,86례)。비교분석량조간실험실급초성검사、관상동맥병변급예후。결과①A 조삼선감유수평급좌심방내경현저고우 B 조[(1.74±1.04) mmol/L비(1.08±0.54) mmol/L,(42±5) mm 비(39±6) mm,P <0.05혹 P <0.01],이A조좌심실사혈분수현저저우B조[(46±14)%비(52±10)%,P<0.05]。②A조환자일급종점급이급종점사건적발생솔균현저고우B조[24.0%(6례)비9.2%(8례),64.0%(16례)비35.6%(31례),P<0.05]。결론억제뇨산수평적승고대우개선노년급성심기경사환자적예후가능구유중요의의。
Objective To investigate the changes of serum uric acid level on prognosis of elderly patients with acute myocardial infarction .Methods A total of 110 elderly patients with acute myocardial infarction admitted in the Affiliated Hospital of Inner Mongolia Medical University from Dec .2012 to Nov. 2013 were given detection of uric acid levels.Men with uric acid level of >420 μmol/L,and women with uric acid level of >357 μmol/L were defined as hyperuricemia.According to the criteria of hyperuricemia, patients were divided into hyperuricemia group(group A) and normal uric acid group(group B).Results of laboratory and ultrasonography examination, conditions of coronary artery disease and prognosis of the two groupswerecompared.Results ①TriglyceridelevelandleftatrialdiameterofgroupAweresignificantly higher than those of group B [(1.74 ±1.04) mmol/L vs (1.08 ±0.54) mmol/L, (42 ±5) mm vs (39 ±6) mm,P<0.05 or P<0.01].While the left ventricular ejection fraction of group A was significantly lower than that of group B[(46 ±14)% vs (52 ±10)%,P<0.05].② In group A,incidences of primary endpoint and secondary endpoint events,acute heart failure,cardiogenic shock and heart failure readmission were significantly higher than those of group B [24.0%(6 cases) vs 9.2%(8 cases),64.0%(16 cases) vs 35.6%(31 cases),P<0.05].Conclusion Inhibition of uric acid level has great significance in improving the prognosis of elderly patients with acute myocardial infarction .