微生物学免疫学进展
微生物學免疫學進展
미생물학면역학진전
PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY
2015年
4期
44-47
,共4页
陆献蒿%梁小凤%邓积广%田红艳
陸獻蒿%樑小鳳%鄧積廣%田紅豔
륙헌호%량소봉%산적엄%전홍염
手足口病%病原学%流行病学%肠道病毒71型
手足口病%病原學%流行病學%腸道病毒71型
수족구병%병원학%류행병학%장도병독71형
Hand foot and mouth disease%Etiology%Epidemiology%EV71
目的：了解2011—2014年百色市重症手足口病的流行病学及病原学特点，为预防和控制重症手足口病提供依据。方法收集2011—2014年百色市重症手足口病疫情资料，进行描述性流行病学分析；采用实时荧光定量PCR方法对手足口病重症病例标本进行肠道病毒通用型、肠道病毒71型和柯萨奇病毒A16型核酸检测。结果2011—2014年百色市共报告手足口病105900例，其中重症手足口病537例，重症率为0．51％；死亡35例，病死率为0．03％。重症手足口病发病主要集中在每年的4—5月；3岁以下重症病例占重症病例总数的88．27％，男女性别比为1．44∶1；散居儿童是主要的发病人群（75．98％）；患者主要集中在平果县、田东县、田阳县、右江区等右江河谷一带；重症手足口病阳性患者中，肠道病毒71型占77．51％，柯萨奇病毒A16型占5．15％，其他肠道病毒占17．34％。结论2011—2014年百色市重症手足口病多发于3岁以下的散居儿童，发病季节主要集中在4—5月，病原体以肠道病毒71型为主。
目的：瞭解2011—2014年百色市重癥手足口病的流行病學及病原學特點，為預防和控製重癥手足口病提供依據。方法收集2011—2014年百色市重癥手足口病疫情資料，進行描述性流行病學分析；採用實時熒光定量PCR方法對手足口病重癥病例標本進行腸道病毒通用型、腸道病毒71型和柯薩奇病毒A16型覈痠檢測。結果2011—2014年百色市共報告手足口病105900例，其中重癥手足口病537例，重癥率為0．51％；死亡35例，病死率為0．03％。重癥手足口病髮病主要集中在每年的4—5月；3歲以下重癥病例佔重癥病例總數的88．27％，男女性彆比為1．44∶1；散居兒童是主要的髮病人群（75．98％）；患者主要集中在平果縣、田東縣、田暘縣、右江區等右江河穀一帶；重癥手足口病暘性患者中，腸道病毒71型佔77．51％，柯薩奇病毒A16型佔5．15％，其他腸道病毒佔17．34％。結論2011—2014年百色市重癥手足口病多髮于3歲以下的散居兒童，髮病季節主要集中在4—5月，病原體以腸道病毒71型為主。
목적：료해2011—2014년백색시중증수족구병적류행병학급병원학특점，위예방화공제중증수족구병제공의거。방법수집2011—2014년백색시중증수족구병역정자료，진행묘술성류행병학분석；채용실시형광정량PCR방법대수족구병중증병례표본진행장도병독통용형、장도병독71형화가살기병독A16형핵산검측。결과2011—2014년백색시공보고수족구병105900례，기중중증수족구병537례，중증솔위0．51％；사망35례，병사솔위0．03％。중증수족구병발병주요집중재매년적4—5월；3세이하중증병례점중증병례총수적88．27％，남녀성별비위1．44∶1；산거인동시주요적발병인군（75．98％）；환자주요집중재평과현、전동현、전양현、우강구등우강하곡일대；중증수족구병양성환자중，장도병독71형점77．51％，가살기병독A16형점5．15％，기타장도병독점17．34％。결론2011—2014년백색시중증수족구병다발우3세이하적산거인동，발병계절주요집중재4—5월，병원체이장도병독71형위주。
Objective To study the epidemiologic and etiologic features of severe hand-foot-mouth disease ( HFMD ) in Baise City from 2011 to 2014, and to provide basis for its prevention and control.Methods Collecting the information a-bout severe HFMD in Baise City from 2011 to 2014, and carrying out the descriptive epidemiological analysis.The real-time fluorescent quantitative PCR( RTFQ-PCR) was used to detected the nuclear acid of commodity enterovirus,Enterovirus 71 and Coxsackie virus A16.Result 105 900 HFMD cases were reported in Baise City, in which there were 537 cases of severe HFMD, the severe rate was 0.51%;there were 35 cases died, the death rate was 0.03%.The severe HFMD main-ly happened in April and May.The most of patients with severe HFMD were the children under 3 years old, accounted for 88.27%, in which the rate between male and female was 1.44 ∶1.The main patients were those children lived seperated-ly.These patients were almost from Youjiang river valley area, such as Pingguo County, Tiandong County, Tianyang Coun-ty and Youjiang Area and so on.Among the severe cases, the enterovirus 71 infectious cases accounted for 77.51%, the Coxsackie virus A16 infectious cases accounted for 5.15%and other enterovirus accounted for 17.34%.Conclusion Se-vere HFMD had happened in the children under 3 years old and lived seperatedly in Baise City between 2011 and 2014, the epidemiologic peak months were in April and May.The main pathogen was EV71.
