CAJ | 학술논문

目的：了解当地女性细菌性阴道病（ BV）患者中阴道加德纳菌（ GV）的感染情况以及GV对常用抗菌药物的敏感性，为BV的诊断和治疗提供依据。方法对收集的492例BV患者和151例正常健康妇女的阴道分泌物进行GV的分离培养与鉴定，并对分离菌进行常用抗菌药物敏感性试验。结果492例BV患者GV阳性率为27．8％，健康妇女GV阳性率为7．9％，两者比较差异有统计学意义（ P＜0．05）。分离的GV对万古霉素和克林霉素均较敏感，对头孢噻肟、四环素、左氧氟沙星、氨苄青霉素、红霉素、甲硝唑的敏感性依次降低。结论 GV为当地BV患者的重要病原菌之一，且对万古霉素和克林霉素均较敏感，对甲硝唑的敏感性最低。
목적：료해당지녀성세균성음도병（ BV）환자중음도가덕납균（ GV）적감염정황이급GV대상용항균약물적민감성，위BV적진단화치료제공의거。방법대수집적492례BV환자화151례정상건강부녀적음도분비물진행GV적분리배양여감정，병대분리균진행상용항균약물민감성시험。결과492례BV환자GV양성솔위27．8％，건강부녀GV양성솔위7．9％，량자비교차이유통계학의의（ P＜0．05）。분리적GV대만고매소화극림매소균교민감，대두포새우、사배소、좌양불사성、안변청매소、홍매소、갑초서적민감성의차강저。결론 GV위당지BV환자적중요병원균지일，차대만고매소화극림매소균교민감，대갑초서적민감성최저。
Objective To understand the infection status of Gardnrella vaginallis ( GV) in female, and to keep abreast of the sensitivity of GV to antibiotics in common use, to provide the scientific basis for clinical diagnosis and treatment. Methods 492vaginalsecretionsamplesand151sampleswerecollectedfrombacterialvaginosis(BV)patientsand healthy female adults respectively, and then GV were isolated and characterized.The bacterial antibiotic sensitivities were detected.Results The positive rate of 492 cases of BV patients is 27.8%, and the positive rate of control woman is 7.9%( P<0.001) .The difference between two groups is of the statistical significance.The isolated GV strains are sensi-tive to vancomycin and clindamycin with higher level.In regular sequence of antibiotic sensitivities from high to low is cefo-taxime, tetracycline, levofloxacin, ampicillin, erythromycin and metronidazole.Conclusion GV is one of important pathogens of BV, and it is higher sensitive to vancomycin and clindamycin, and it is the lowest sensitive to metronidazole.