暨南大学学报（自然科学与医学版）
暨南大學學報（自然科學與醫學版）
기남대학학보（자연과학여의학판）
JOURNAL OF JINAN UNIVERSITY（NATURAL SCIENCE & MEDICINE EDITION）
2015年
3期
251-255
,共5页
大脑中动脉%基底动脉%症状性狭窄%狭窄程度%进展性卒中
大腦中動脈%基底動脈%癥狀性狹窄%狹窄程度%進展性卒中
대뇌중동맥%기저동맥%증상성협착%협착정도%진전성졸중
middle cerebral artery%basilar artery%symptomatic stenosis%stenosis grading%stroke in progression
目的：通过经颅多普勒超声（TCD）检测症状性大脑中动脉（MCA）、基底动脉（BA）狭窄及狭窄程度与进展性卒中的相关性．方法：回顾分析164例 MCA 或 BA 供血区急性脑梗死病人资料．采用 TCD 诊断症状性 MCA、BA 狭窄并判定其狭窄程度．观察症状性 MCA、BA 狭窄及其严重程度与进展性卒中的相关性．结果：症状性狭窄组进展性卒中发生率（57.70％）明显高于非症状性狭窄组（36.60％）．Logistic 回归显示症状性 MCA 或 BA 狭窄、女性是进展性卒中的危险因素，OR 值分别为2.560、2.010．无狭窄及无症状性狭窄、轻度、中度、重度症状性 MCA、BA 狭窄组进展性卒中发生率分别为37.2％、46.1％、65.2％和61.9％，各组间进展性卒中发生率有显著性差异．中度症状性狭窄组进展性卒中危险性最高．有良好侧枝循环代偿的重度狭窄病人的进展性卒中发生率为33.33％，低于无明显侧枝循环代偿者的88.88％，但无统计学差异．结论：症状性 MCA、BA 狭窄是进展性卒中的独立危险因素．狭窄程度与进展性卒中密切相关，中度症状性 MCA、BA 狭窄发生进展性卒中危险性最高．良好侧支循环可能是重度症状性 MCA 狭窄进展危险较中度狭窄低的原因．
目的：通過經顱多普勒超聲（TCD）檢測癥狀性大腦中動脈（MCA）、基底動脈（BA）狹窄及狹窄程度與進展性卒中的相關性．方法：迴顧分析164例 MCA 或 BA 供血區急性腦梗死病人資料．採用 TCD 診斷癥狀性 MCA、BA 狹窄併判定其狹窄程度．觀察癥狀性 MCA、BA 狹窄及其嚴重程度與進展性卒中的相關性．結果：癥狀性狹窄組進展性卒中髮生率（57.70％）明顯高于非癥狀性狹窄組（36.60％）．Logistic 迴歸顯示癥狀性 MCA 或 BA 狹窄、女性是進展性卒中的危險因素，OR 值分彆為2.560、2.010．無狹窄及無癥狀性狹窄、輕度、中度、重度癥狀性 MCA、BA 狹窄組進展性卒中髮生率分彆為37.2％、46.1％、65.2％和61.9％，各組間進展性卒中髮生率有顯著性差異．中度癥狀性狹窄組進展性卒中危險性最高．有良好側枝循環代償的重度狹窄病人的進展性卒中髮生率為33.33％，低于無明顯側枝循環代償者的88.88％，但無統計學差異．結論：癥狀性 MCA、BA 狹窄是進展性卒中的獨立危險因素．狹窄程度與進展性卒中密切相關，中度癥狀性 MCA、BA 狹窄髮生進展性卒中危險性最高．良好側支循環可能是重度癥狀性 MCA 狹窄進展危險較中度狹窄低的原因．
목적：통과경로다보륵초성（TCD）검측증상성대뇌중동맥（MCA）、기저동맥（BA）협착급협착정도여진전성졸중적상관성．방법：회고분석164례 MCA 혹 BA 공혈구급성뇌경사병인자료．채용 TCD 진단증상성 MCA、BA 협착병판정기협착정도．관찰증상성 MCA、BA 협착급기엄중정도여진전성졸중적상관성．결과：증상성협착조진전성졸중발생솔（57.70％）명현고우비증상성협착조（36.60％）．Logistic 회귀현시증상성 MCA 혹 BA 협착、녀성시진전성졸중적위험인소，OR 치분별위2.560、2.010．무협착급무증상성협착、경도、중도、중도증상성 MCA、BA 협착조진전성졸중발생솔분별위37.2％、46.1％、65.2％화61.9％，각조간진전성졸중발생솔유현저성차이．중도증상성협착조진전성졸중위험성최고．유량호측지순배대상적중도협착병인적진전성졸중발생솔위33.33％，저우무명현측지순배대상자적88.88％，단무통계학차이．결론：증상성 MCA、BA 협착시진전성졸중적독립위험인소．협착정도여진전성졸중밀절상관，중도증상성 MCA、BA 협착발생진전성졸중위험성최고．량호측지순배가능시중도증상성 MCA 협착진전위험교중도협착저적원인．
Aim:Using transcranial Doppler (TCD)sonography for evaluation of artery stenosis,to study the correlations of symptomatic stenosis in middle cerebral artery (MCA)and basilar artery (BA) to stroke in progression (SIP).Methods:Patients (164 cases)with acute cerebral infarction in MCA or BA district were included in this study.MCA and BA stenosis as well as the stenosis grading were evalua-ted by using TCD sonohraphy.The correlations of symptomatic MCA,BA stenosis to SIP were analyzed with software SPSS 10.0.Results:The incidence rate of SIP in patients with symptomatic stenosis (57.70%)was significantly higher than that with non-intracranial artery stenosis and asymptomatic ste-nosis (36.60%).Logistic regression analysis showed that symptomatic MCA and BA stenosis(OR =2.560)and female(OR =2.010)were the risk factors of SIP.The incidence of SIP in patients with non- <br> intracranial artery stenosis and asymptomatic artery stenosis,mild,moderate and severe artery stenosis were 37.2%、46.1%、65.2% and 61.9% respectively,with significant differences.The risk of SIP is highest in moderate symptomatic MCA or BA stenosis.The incidence of SIP In severe stenosis patients with collateral circulation(33.33%)was lower than that in none collateral circulation patients,but with-out statistic difference.Conclusion:Symptomatic MCA or BA stenosis is an independent risk factor of SIP.The stenosis grading is closely related to SIP.The risk for SIP is highest in moderate symptomatic MCA or BA stenosis,and higher in severe symptomatic stenosis,than those with mild stenosis.The low-est risk for SIP is in patients with asymptomatic stenosis or none intracranial artery stenosis.Collateral circulation maybe the cause of relative lower risk for SIP in severe symptomatic stenosis.
