医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
11期
2105-2106,2107
,共3页
前置胎盘%产后出血%卡前列素氨丁三醇注射液%缩宫素
前置胎盤%產後齣血%卡前列素氨丁三醇註射液%縮宮素
전치태반%산후출혈%잡전렬소안정삼순주사액%축궁소
Placenta previa%Postpartum hemorrhage%Carboprost tromethamine injection%Oxytocin
目的:比较卡前列素氨丁三醇注射液与缩宫素对预防前置胎盘产后出血的临床效果。方法选取2009年10月至2013年12月洪湖市妇幼保健院治疗的87例胎盘前置的孕产妇,按随机数字表法分为缩宫素组(44例)和卡前列素氨丁三醇注射液组(43例)。缩宫素组应用缩宫素治疗,卡前列素氨丁三醇注射液组应用卡前列素氨丁三醇注射液治疗(250μg,子宫体注射),比较两组孕产妇在术中、术后2、24 h的出血情况、血红蛋白变化及不良反应发生情况。结果缩宫素组分娩术中、术后2 h、术后24 h出血量分别为(455±36) mL、(423±46) mL、(357±24) mL,卡前列素氨丁三醇注射液组分娩术中、术后2 h、术后24 h 出血量分别为(403±31) mL、(227±43) mL、(193±23) mL。与缩宫素组相比,卡前列素氨丁三醇注射液组各阶段出血量均较少,差异有统计学意义(P<0.05)。两组均出现血压一过性升高、恶心、面部潮红等不良反应,但两组不良反应发生率比较差异无统计学意义( P>0.05)。结论前置胎盘孕产妇注射卡前列素氨丁三醇注射液对预防产后出血具有良好的作用。
目的:比較卡前列素氨丁三醇註射液與縮宮素對預防前置胎盤產後齣血的臨床效果。方法選取2009年10月至2013年12月洪湖市婦幼保健院治療的87例胎盤前置的孕產婦,按隨機數字錶法分為縮宮素組(44例)和卡前列素氨丁三醇註射液組(43例)。縮宮素組應用縮宮素治療,卡前列素氨丁三醇註射液組應用卡前列素氨丁三醇註射液治療(250μg,子宮體註射),比較兩組孕產婦在術中、術後2、24 h的齣血情況、血紅蛋白變化及不良反應髮生情況。結果縮宮素組分娩術中、術後2 h、術後24 h齣血量分彆為(455±36) mL、(423±46) mL、(357±24) mL,卡前列素氨丁三醇註射液組分娩術中、術後2 h、術後24 h 齣血量分彆為(403±31) mL、(227±43) mL、(193±23) mL。與縮宮素組相比,卡前列素氨丁三醇註射液組各階段齣血量均較少,差異有統計學意義(P<0.05)。兩組均齣現血壓一過性升高、噁心、麵部潮紅等不良反應,但兩組不良反應髮生率比較差異無統計學意義( P>0.05)。結論前置胎盤孕產婦註射卡前列素氨丁三醇註射液對預防產後齣血具有良好的作用。
목적:비교잡전렬소안정삼순주사액여축궁소대예방전치태반산후출혈적림상효과。방법선취2009년10월지2013년12월홍호시부유보건원치료적87례태반전치적잉산부,안수궤수자표법분위축궁소조(44례)화잡전렬소안정삼순주사액조(43례)。축궁소조응용축궁소치료,잡전렬소안정삼순주사액조응용잡전렬소안정삼순주사액치료(250μg,자궁체주사),비교량조잉산부재술중、술후2、24 h적출혈정황、혈홍단백변화급불량반응발생정황。결과축궁소조분면술중、술후2 h、술후24 h출혈량분별위(455±36) mL、(423±46) mL、(357±24) mL,잡전렬소안정삼순주사액조분면술중、술후2 h、술후24 h 출혈량분별위(403±31) mL、(227±43) mL、(193±23) mL。여축궁소조상비,잡전렬소안정삼순주사액조각계단출혈량균교소,차이유통계학의의(P<0.05)。량조균출현혈압일과성승고、악심、면부조홍등불량반응,단량조불량반응발생솔비교차이무통계학의의( P>0.05)。결론전치태반잉산부주사잡전렬소안정삼순주사액대예방산후출혈구유량호적작용。
Objective To compare the prevention and treatment effect between carboprost tromethamine injection and oxytocin injection on postpartum hemorrhage in placenta previa .Methods A total of 87 cases of pregnant women with placenta previa admitted in Honghu Maternal and Child Health Care Hospital from Oct.2009 to Dec.2013 were selected and divided into two groups according to random number table.Patients in oxytocin group(44 cases) were treated with oxytocin,while patients in carboprost tromethamine group(43 cases) were treated with carboprost tromethamine injection(250 μg,uterine body injection).Blood loss vol-umes and hemoglobin level changes during the operation,2 hours and 24 hours after operation of the two groups were compared.Results The blood loss volumes during the operation,2 hours and 24 hours after operation of the oxytocin group were (455 ±36) mL,(423 ±46) mL and (357 ±24) mL respectively,while those of the carboprost tromethamine group were ( 403 ±31 ) mL, ( 227 ±43 ) mL and ( 193 ±23 ) mL respectively.The blood loss volumes of the carboprost tromethamine group were significantly less than the oxytocin group at different phases mentioned above ( P<0 .05 ) .There were incidences of adverse reactions such as transient rise in blood pressure,nausea and facial blushing in two groups,although there were no sta-tistically significant differences of such incidences between the two groups(P>0.05).Conclusion Prophy-lactic use of carboprost tromethamine injection in pregnant women with placenta previa can significantly reduce the risk of postoperative bleeding.