医学影像学杂志
醫學影像學雜誌
의학영상학잡지
JOURNAL OF MEDICAL IMAGING
2015年
6期
958-961
,共4页
王国华%石艳艳%宋修峰%刘光震%冯磊%王弘岩%徐志鹏%杨璇
王國華%石豔豔%宋脩峰%劉光震%馮磊%王弘巖%徐誌鵬%楊璇
왕국화%석염염%송수봉%류광진%풍뢰%왕홍암%서지붕%양선
氢质子磁共振波谱%颅脑肿瘤%肿瘤周围区%磁共振成像
氫質子磁共振波譜%顱腦腫瘤%腫瘤週圍區%磁共振成像
경질자자공진파보%로뇌종류%종류주위구%자공진성상
Proton magnetic resonance spectroscopy%Brain tumors%Peritumoral area%Magnetic resonance imaging
目的:探讨肿瘤周围的多体素氢质子磁共振波谱(1 H‐MRS)在脑星形细胞瘤、脑转移瘤等颅内常见肿瘤中的诊断及鉴别诊断价值。方法收集本院经手术、活检病理证实的颅脑肿瘤患者66例。其中低级别星形细胞瘤(Ⅰ~Ⅱ级)19例,高级别星形细胞瘤(Ⅲ~Ⅳ级)17例;脑转移瘤30例。采用美国 GE 公司3.0T MRI 扫描仪对所有患者行颅脑常规 MRI 及1 H‐MRS 检查。检测、计算、分析肿瘤周围及健侧相应区域的生化代谢物及其比值,包括 Cho/ Cr 、Cho/NAA 、NAA /Cr 及 MI ,同时进行加以比较对照。结果高级别星形细胞瘤的瘤周水肿区 Cho/Cr 比值明显高于低级别星形细胞瘤、脑转移瘤( P <0.05);其 Cho/NAA 比值明显高于低级别星形细胞瘤及脑转移瘤( P <0.05)。低级别星形细胞瘤瘤周 NAA/Cr 比值明显高于高级别星形细胞瘤( P <0.05)。低级别星形细胞瘤与脑转移瘤比较各代谢物比值均无统计学意义。 MI 值各肿瘤间比较无统计学意义。结论肿瘤周围的 Cho/Cr 、Cho/NAA 比值对脑内低级别及高级别星形细胞瘤、脑转移瘤等的诊断及鉴别诊断具有较高的临床应用价值。
目的:探討腫瘤週圍的多體素氫質子磁共振波譜(1 H‐MRS)在腦星形細胞瘤、腦轉移瘤等顱內常見腫瘤中的診斷及鑒彆診斷價值。方法收集本院經手術、活檢病理證實的顱腦腫瘤患者66例。其中低級彆星形細胞瘤(Ⅰ~Ⅱ級)19例,高級彆星形細胞瘤(Ⅲ~Ⅳ級)17例;腦轉移瘤30例。採用美國 GE 公司3.0T MRI 掃描儀對所有患者行顱腦常規 MRI 及1 H‐MRS 檢查。檢測、計算、分析腫瘤週圍及健側相應區域的生化代謝物及其比值,包括 Cho/ Cr 、Cho/NAA 、NAA /Cr 及 MI ,同時進行加以比較對照。結果高級彆星形細胞瘤的瘤週水腫區 Cho/Cr 比值明顯高于低級彆星形細胞瘤、腦轉移瘤( P <0.05);其 Cho/NAA 比值明顯高于低級彆星形細胞瘤及腦轉移瘤( P <0.05)。低級彆星形細胞瘤瘤週 NAA/Cr 比值明顯高于高級彆星形細胞瘤( P <0.05)。低級彆星形細胞瘤與腦轉移瘤比較各代謝物比值均無統計學意義。 MI 值各腫瘤間比較無統計學意義。結論腫瘤週圍的 Cho/Cr 、Cho/NAA 比值對腦內低級彆及高級彆星形細胞瘤、腦轉移瘤等的診斷及鑒彆診斷具有較高的臨床應用價值。
목적:탐토종류주위적다체소경질자자공진파보(1 H‐MRS)재뇌성형세포류、뇌전이류등로내상견종류중적진단급감별진단개치。방법수집본원경수술、활검병리증실적로뇌종류환자66례。기중저급별성형세포류(Ⅰ~Ⅱ급)19례,고급별성형세포류(Ⅲ~Ⅳ급)17례;뇌전이류30례。채용미국 GE 공사3.0T MRI 소묘의대소유환자행로뇌상규 MRI 급1 H‐MRS 검사。검측、계산、분석종류주위급건측상응구역적생화대사물급기비치,포괄 Cho/ Cr 、Cho/NAA 、NAA /Cr 급 MI ,동시진행가이비교대조。결과고급별성형세포류적류주수종구 Cho/Cr 비치명현고우저급별성형세포류、뇌전이류( P <0.05);기 Cho/NAA 비치명현고우저급별성형세포류급뇌전이류( P <0.05)。저급별성형세포류류주 NAA/Cr 비치명현고우고급별성형세포류( P <0.05)。저급별성형세포류여뇌전이류비교각대사물비치균무통계학의의。 MI 치각종류간비교무통계학의의。결론종류주위적 Cho/Cr 、Cho/NAA 비치대뇌내저급별급고급별성형세포류、뇌전이류등적진단급감별진단구유교고적림상응용개치。
Objective To evaluate the clinical value of MR spectroscopy of peritumoral area in intracranial neoplasm (the brain astrocytomas ,metastatic tumors of the brain) .Methods Sixty‐six cases with brain neoplasm were collected from the Affiliated Hospital of Qingdao University .All the patients ,who were confirmed by pathology ,underwent proton MR Spectroscopy before stereotactic biopsy ,or operation .Results The Cho/Cr ratio of peritumoral area in high‐grade astro‐cytoma was significantly higher than that in low grade astrocytoma and brain metastatic tumors ( P < 0 .05) ,and the Cho/NAA ratio was significantly higher than that of low‐grade astrocytic tumor and brain metastases ( P < 0 .05) .The NAA/Cr ratio of peritumoral area in peritumoral NAA/Cr ratio was significantly higher than that in high‐grade astrocytoma ( P< 0.05) .The peritumoral metabolite ratios between low grade astrocytoma and brain metastases were not statistically sig‐nificant difference .The value of MI showed no statistical significant different between the four tumors .Conclusion MR spectroscopy of peritumoral area has significant value in detecting and differentiating brain tumors (such as the low grade astrocytoma ,high‐grade astrocytoma and metastatic tumors of the brain etc .) .