CAJ | 학술논문

目的：分析2型糖尿病患者在胰岛素强化治疗的模式下发生夜间低血糖的危险因素及其预防措施。方法对50例于北京中医药大学附属护国寺中医医院进行治疗的2型糖尿病患者采用胰岛素强化治疗，通过Logistic回归性分析对各因素与夜间低血糖的相关性并进行统计学分析。结果 Logistic 回归分析结果显示，年龄（OR ＝10.593，95％CI 1.102～114.634）、病程（OR ＝1.672，95％CI 0.916～2.869）、空腹C肽（OR＝0.761，95％CI 0.331～1.703）、尿白蛋白（OR＝5.476，95％CI 1.352～23.821）是2型糖尿病夜间发生低血糖的危险因素（ P＜0.05）。结论患者的年龄、体质指数、病程及空腹C肽和尿白蛋白水平为夜间发生低血糖的危险因素，对其进行监控，有利于减少夜间低血糖的发生。
목적：분석2형당뇨병환자재이도소강화치료적모식하발생야간저혈당적위험인소급기예방조시。방법대50례우북경중의약대학부속호국사중의의원진행치료적2형당뇨병환자채용이도소강화치료，통과Logistic회귀성분석대각인소여야간저혈당적상관성병진행통계학분석。결과 Logistic 회귀분석결과현시，년령（OR ＝10.593，95％CI 1.102～114.634）、병정（OR ＝1.672，95％CI 0.916～2.869）、공복C태（OR＝0.761，95％CI 0.331～1.703）、뇨백단백（OR＝5.476，95％CI 1.352～23.821）시2형당뇨병야간발생저혈당적위험인소（ P＜0.05）。결론환자적년령、체질지수、병정급공복C태화뇨백단백수평위야간발생저혈당적위험인소，대기진행감공，유리우감소야간저혈당적발생。
Objective To analyze the risk factors of nocturnal hypoglycemia in patients with type 2 dia-betes under intensive insulin therapies and related preventive measures .Methods A total of 50 patients with type 2 diabetes were administered intensive insulin therapies in Huguosi Hospital of Traditional Chinese Medicine Affiliated to Beijing University of Traditional Chinese Medicine .Risk factors of nocturnal hypogly-cemia were analyzed by logistic regression analysis.Results Results of logistic regression analysis showed that age(OR=10.593,95%CI 1.102-114.634),course of the disease(OR =1.672, 95%CI 0.916-2.869),fasting C-peptide(OR =0.761,95%CI 0.331-1.703),urinary albumin(OR =5.476,95%CI 1.352-23.821) were the risk factors of nocturnal hypoglycemia in patients with diabetes(P <0.05). Conclusion Age,body mass index,course of the disease,fasting C-peptide and urinary albumin level of the patients are the risk factors of nocturnal hypoglycemia in patients with type 2 diabetes,monitoring on such factors is helpful to reduce the incidence of nocturnal hypoglycemia .