CAJ | 학술논문

目的：探讨幽门螺杆菌（Hp）感染与晕动病发病的相关性，观察晕车组根除 Hp 后晕车症状改善情况。方法从消化内科慢性胃炎门诊人群中抽查765例，调查患者年龄、职别、疾病史、晕车症状及进行14 C 呼气试验检测，并对153例晕车且14 C 呼气试验阳性的患者采用四联疗法根除 Hp，观察 Hp 根除前后晕车症状的变化，根据调查结果进行分析。结果765例患者中，Hp 阳性384例，Hp 总阳性率50．20％，发生晕车者213例，晕车者 Hp 阳性153例，Hp 阳性率71．83％（153／213）。不晕车者 Hp 阳性231例，不晕车组阳性率41．85％（231／552），两组比较差异有统计学意义（χ2＝55．27，P ＜0．05）。Hp 阳性且晕车153例中，76例采用四联疗法根除 Hp，1年后晕车症状改善11例，77例未予根除 Hp，1年后晕车症状改善2例，两者比较差异有统计学意义（χ2＝6．94，P ＜0．05）。结论Hp 感染与晕动病的发生有一定相关性，根除 Hp 可能有利于改善晕车症状。
목적：탐토유문라간균（Hp）감염여훈동병발병적상관성，관찰훈차조근제 Hp 후훈차증상개선정황。방법종소화내과만성위염문진인군중추사765례，조사환자년령、직별、질병사、훈차증상급진행14 C 호기시험검측，병대153례훈차차14 C 호기시험양성적환자채용사련요법근제 Hp，관찰 Hp 근제전후훈차증상적변화，근거조사결과진행분석。결과765례환자중，Hp 양성384례，Hp 총양성솔50．20％，발생훈차자213례，훈차자 Hp 양성153례，Hp 양성솔71．83％（153／213）。불훈차자 Hp 양성231례，불훈차조양성솔41．85％（231／552），량조비교차이유통계학의의（χ2＝55．27，P ＜0．05）。Hp 양성차훈차153례중，76례채용사련요법근제 Hp，1년후훈차증상개선11례，77례미여근제 Hp，1년후훈차증상개선2례，량자비교차이유통계학의의（χ2＝6．94，P ＜0．05）。결론Hp 감염여훈동병적발생유일정상관성，근제 Hp 가능유리우개선훈차증상。
Objective To study the helicobacter pylori(HP)infection and incidence of motion sickness,and observe the improment of motion sickness symptoms of motion sickness group after eradication of helicobacter pylori. Methods Random drawing from chronic gastritis of digestive diseases outpatient spot in the crowd of 765 people, which were investigated through the age,job title,medical history,symptoms of motion sickness and 14 C -UBT test. 153 cases of motion sickness with 14 C -UBT test positive were observed before and after helicobacter pylori eradication of the change of motion sickness symptoms by using quadruple therapy in patients with helicobacter pylori eradication, results were analyzed according to the survey.Results 765 people,384 cases HP positive,HP total positive rate 50.20%.motion sickness occurred in 213 cases,motion sickness was 153 cases HP positive,HP positive rate 71.83%(153 /213);Without HP positive,231 cases of motion sickness,positive rate of motion sickness group were 41.85%(231 /552),which were similar between the two groups with statistically significant(χ2 =55.27,P <0.05). In the HP positive and carsick 153 cases,76 cases of using quadruple therapy for the eradication of helicobacter pylori,and motion sickness symptoms improved were 11 cases 1 years later.The eradication of helicobacter pylori was not used in 77 cases,in which motion sickness symptoms improved for 2 cases 1 year later.And the comparative difference was statistically significant(χ2 =6.94,P <0.05).Conclusion HP infection has certain correlation with the incidence of motion sickness,the eradication of helicobacter pylori may be beneficial to improve the symptoms of motion sickness.