CAJ | 학술논문

目的:研究分析胃食管结合部癌患者行保留胃窦空肠间置双通道手术后对生存质量及预后的影响. 方法:从2012年4月至2013年4月,选择在我院同意手术治疗的胃食管结合部癌患者104例进行研究. 根据数字法随机对104例患者分组,分为观察组52例及对照组52例. 对照组实施传统的胃切除及消化道重建手术,观察组则实施保留胃窦空肠间置双通道手术,对比不同术式患者治疗前后的生存质量,比较两组的手术情况和预后情况. 结果:两组患者治疗后的Spitzer 评分和QOL评分均增加,但观察组的增加幅度显著大于对照组,差异均有统计学意义(均P<0.05). 观察组与对照组在腹壁切口长度和消化道重建时间,以及肛门排气时间和住院时间等方面相比,差异均无统计学意义(均P>0.05). 观察组在癌症转移、复发及死亡等方面预后与对照组相比,差异均无统计学意义(均P>0.05). 结论:对于患有胃食管结合部癌的患者实施保留胃窦的空肠间置双通道术式,能够有效改善患者的生存质量,且预后状态较好,值得在临床上推广应用.
목적:연구분석위식관결합부암환자행보류위두공장간치쌍통도수술후대생존질량급예후적영향. 방법:종2012년4월지2013년4월,선택재아원동의수술치료적위식관결합부암환자104례진행연구. 근거수자법수궤대104례환자분조,분위관찰조52례급대조조52례. 대조조실시전통적위절제급소화도중건수술,관찰조칙실시보류위두공장간치쌍통도수술,대비불동술식환자치료전후적생존질량,비교량조적수술정황화예후정황. 결과:량조환자치료후적Spitzer 평분화QOL평분균증가,단관찰조적증가폭도현저대우대조조,차이균유통계학의의(균P<0.05). 관찰조여대조조재복벽절구장도화소화도중건시간,이급항문배기시간화주원시간등방면상비,차이균무통계학의의(균P>0.05). 관찰조재암증전이、복발급사망등방면예후여대조조상비,차이균무통계학의의(균P>0.05). 결론:대우환유위식관결합부암적환자실시보류위두적공장간치쌍통도술식,능구유효개선환자적생존질량,차예후상태교호,치득재림상상추엄응용.
Objective:To study impact of quality of life and prognosis after operation of gastroesophage-al junction carcinoma patients with retained sinuses ventriculi distal gastric jejunum by dual channel.Meth-od:From April 2012 to April 2013, in our hospital agreed to the integration of a surgical treatment of gas-troesophageal junction carcinoma patients (104 cases) were studied.According to the digital method 104 ca-ses of patients, 52 cases were divided into observation group and control group,each with 52 cases.Control group was treated with traditional resection of the stomach and digestive tract reconstruction surgery , observa-tion group retained sinuses ventriculi distal gastric jejunum by dual channel operation, contrasted different operative methods before and after treatment in the quality of survival, compared two groups of surgery and prognosis.Result: Two groups after treatment in patients with Spitzer, scoring and QOL scores increased, but the increase of the observation group was significantly greater than the control group, the differences were statistically significant ( all P <0.05) .Observation group and control group in the incision length and diges-tive tract reconstruction, and anal exhaust time and hospital stay compared with difference had no statistical significance ( P >0.05) .Observation group in the prognosis of cancer metastasis and recurrence and death compared with control group, there were no statistically significant difference ( P >0.05) .Conclusion:For patients with gastroesophageal junction carcinoma treated with retained sinuses ventriculi distal gastric jeju-num by dual channel operation can effectively improve the patient's quality of life, and has better prognosis, It is worth popularization and application in clinic.