中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
13期
1921-1923
,共3页
多囊卵巢综合征%不育(女)雌性%宫腔镜检查%腹腔镜检查
多囊卵巢綜閤徵%不育(女)雌性%宮腔鏡檢查%腹腔鏡檢查
다낭란소종합정%불육(녀)자성%궁강경검사%복강경검사
Polycystic ovary syndrome%Sterilec(female)%Hysteroscopy%Laparoscopy
目的:探讨宫-腹腔镜联合诊治难治性多囊卵巢综合征合并不孕的必要性和疗效。方法选择多囊卵巢综合征(PCOS)合并不孕患者80例,按随机数字表法分为两组各40例,研究组使用宫-腹腔镜联合诊治,对照组仅单纯使用腹腔镜诊治。比较两组手术前后卵巢、卵泡及血清激素水平变化情况,同时记录两组术后正常排卵率、妊娠率及流产率。结果研究组术后卵泡个数及卵巢体积均较治疗前明显下降,且明显低于对照组,差异均有统计学意义(t =3.82、3.80、3.74、3.75,均 P <0.05)。研究组术后血清 T、LH 及 LH/FSH 较术前明显降低,且明显低于对照组,差异均有统计学意义(t =9.32、4.06、3.80,均 P <0.05)。研究组术后正常排卵率、妊娠率及流产率分别为90.0%、62.5%及7.5%,与对照组的72.5%、50.0%及15.0%差异均有统计学意义(χ2=4.02、4.10、3.90,均 P <0.05)。结论宫-腹腔镜联合诊治 PCOS 合并不孕疗效显著,可有效提高患者术后排卵率及妊娠率,并降低自然流产率,值得临床推广应用。
目的:探討宮-腹腔鏡聯閤診治難治性多囊卵巢綜閤徵閤併不孕的必要性和療效。方法選擇多囊卵巢綜閤徵(PCOS)閤併不孕患者80例,按隨機數字錶法分為兩組各40例,研究組使用宮-腹腔鏡聯閤診治,對照組僅單純使用腹腔鏡診治。比較兩組手術前後卵巢、卵泡及血清激素水平變化情況,同時記錄兩組術後正常排卵率、妊娠率及流產率。結果研究組術後卵泡箇數及卵巢體積均較治療前明顯下降,且明顯低于對照組,差異均有統計學意義(t =3.82、3.80、3.74、3.75,均 P <0.05)。研究組術後血清 T、LH 及 LH/FSH 較術前明顯降低,且明顯低于對照組,差異均有統計學意義(t =9.32、4.06、3.80,均 P <0.05)。研究組術後正常排卵率、妊娠率及流產率分彆為90.0%、62.5%及7.5%,與對照組的72.5%、50.0%及15.0%差異均有統計學意義(χ2=4.02、4.10、3.90,均 P <0.05)。結論宮-腹腔鏡聯閤診治 PCOS 閤併不孕療效顯著,可有效提高患者術後排卵率及妊娠率,併降低自然流產率,值得臨床推廣應用。
목적:탐토궁-복강경연합진치난치성다낭란소종합정합병불잉적필요성화료효。방법선택다낭란소종합정(PCOS)합병불잉환자80례,안수궤수자표법분위량조각40례,연구조사용궁-복강경연합진치,대조조부단순사용복강경진치。비교량조수술전후란소、란포급혈청격소수평변화정황,동시기록량조술후정상배란솔、임신솔급유산솔。결과연구조술후란포개수급란소체적균교치료전명현하강,차명현저우대조조,차이균유통계학의의(t =3.82、3.80、3.74、3.75,균 P <0.05)。연구조술후혈청 T、LH 급 LH/FSH 교술전명현강저,차명현저우대조조,차이균유통계학의의(t =9.32、4.06、3.80,균 P <0.05)。연구조술후정상배란솔、임신솔급유산솔분별위90.0%、62.5%급7.5%,여대조조적72.5%、50.0%급15.0%차이균유통계학의의(χ2=4.02、4.10、3.90,균 P <0.05)。결론궁-복강경연합진치 PCOS 합병불잉료효현저,가유효제고환자술후배란솔급임신솔,병강저자연유산솔,치득림상추엄응용。
Objective To investigate the effect and necessity of hysteroscopy combined with laparoscopy in the diagnosis and treatment of refractory polycystic ovarian syndrome complicated with infertility.Methods 80 cases of patients with polycystic ovary syndrome (PCOS)combined with infertility were randomly divided into two groups with 40 cases in each group.The testing group used hysteroscopy combined with laparoscopy in diagnosis and treatment while the laparoscopy was only used in the control group.The changes of ovary,ovarian follicles and serum hormone level of the two groups which before and after operation were compared,and the data of postoperative normal ovulation rate,pregnancy rate and abortion rate of the two groups were recorded.Results The follicle number and ovarian volume of the testing group were significantly decreased than that before treatment,and were significantly lower than that of the control group,with statistical difference (t =3.82,3.80,3.74,3.75,all P <0.05).The serum T,LH and LH/FSH of the testing group were significantly decreased than the data before surgery,and were significantly lower compared to the control group with statistical difference (t =9.32,4.06,3.80,all P <0.05).The normal ovulation rate,pregnancy rate and abortion rate of the testing group were significantly higher compared to the control group (90.0%,62.5% and 7.5% vs.72.5%,50% and 15%)χ2 =4.02,4.10,3.90,all P <0.05).Conclusion Hyste-roscopy combined with laparoscopy has an obvious curative effect in the diagnosis and treatment of polycystic ovary syndrome combined with infertility,which can effectively improve ovulation rate and pregnancy rate and reduce the abortion rate,is worthy of clinical application.