CAJ | 학술논문

目的：探讨热毒宁治疗慢性阻塞性肺病急性期的疗效。方法74例慢性阻塞性肺病患者随机分为实验组和对照组，每组37例。两组均给予常规治疗，实验组在此基础上给予热毒宁注射液治疗，两组均以10天为1个疗程，并随访1~2周，观察治疗前后两组患者治疗总有效率、FEV1/FVC、FEV占预计值百分比等指标及不良反应发生情况。结果实验组总有效率为81.08%，对照组为56.76%，两组比较，差异具有显著性(P<0.05)；实验组在改善患者临床症状、肺功能等方面均优于对照组，差异具有显著性(P<0.05)。结论热毒宁对慢性阻塞性肺病具有良好的治疗作用，能明显改善患者预后，值得临床推广应用。
목적：탐토열독저치료만성조새성폐병급성기적료효。방법74례만성조새성폐병환자수궤분위실험조화대조조，매조37례。량조균급여상규치료，실험조재차기출상급여열독저주사액치료，량조균이10천위1개료정，병수방1~2주，관찰치료전후량조환자치료총유효솔、FEV1/FVC、FEV점예계치백분비등지표급불량반응발생정황。결과실험조총유효솔위81.08%，대조조위56.76%，량조비교，차이구유현저성(P<0.05)；실험조재개선환자림상증상、폐공능등방면균우우대조조，차이구유현저성(P<0.05)。결론열독저대만성조새성폐병구유량호적치료작용，능명현개선환자예후，치득림상추엄응용。
Objective To investigate the efficacy and safety of Reduning treatment of acute exacerbation phase of chronic obstructive pulmonary. Methods A total of 74 patients with AECOPD were selected and divided randomly into two groups:a treatment group and one control group. The treatment group received Reduning (n=37) for 10 days, while the control group received conventional treatment (n=37) alone for the same duration, respectively, and follow-up of 1 to 2 weeks. To observe the total effective rate of two groups of patients before and after the treatment、FEV1/FVC and FEV1/FVC, FEV take up of the expected target. Results The levels of lung function indexes and adverse drug reactions before and after treatment were compared between groups improved obviously after treatment(P<0.05). The response rates were 81.08%and 56.76%in treatment group and the control groups, respectively. There were significant differences between the two groups in improvement of clinical symptoms(P<0.05). Conclusion The treatment of Reduning has a good treatment effect in treatment of acute exacerbation phase of chronic obstructive pulmonary without adverse reaction. It is worthy of clinical application.