CAJ | 학술논문

目的：探讨不同药物治疗妊娠高血压综合征的临床疗效。方法将144例妊高征患者依据随机数字表法分成两组：对照组采用单纯硫酸镁治疗，观察组采用硫酸镁、硝酸甘油微量泵入治疗。比较两组的临床疗效、血压和24 h尿蛋白量的变化情况以及妊娠结果。结果观察组的总有效率显著高于对照组(90.28%vs 73.61)( P＜0.05)；治疗后观察组患者的舒张压、收缩压、24 h尿蛋白量降幅均显著性大于对照组( P＜0.05)；观察组患者出现胎盘早剥、早产、胎儿窘迫、剖宫产、产后出血、以及新生儿窒息等妊娠结局的概率显著低于对照组( P＜0.05)。结论临床应用硝酸甘油微量泵入辅助硫酸镁治疗妊高征能够明显降低血压、改善妊娠预后。
목적：탐토불동약물치료임신고혈압종합정적림상료효。방법장144례임고정환자의거수궤수자표법분성량조：대조조채용단순류산미치료，관찰조채용류산미、초산감유미량빙입치료。비교량조적림상료효、혈압화24 h뇨단백량적변화정황이급임신결과。결과관찰조적총유효솔현저고우대조조(90.28%vs 73.61)( P＜0.05)；치료후관찰조환자적서장압、수축압、24 h뇨단백량강폭균현저성대우대조조( P＜0.05)；관찰조환자출현태반조박、조산、태인군박、부궁산、산후출혈、이급신생인질식등임신결국적개솔현저저우대조조( P＜0.05)。결론림상응용초산감유미량빙입보조류산미치료임고정능구명현강저혈압、개선임신예후。
Objective To investigate the treatment of clinical curative effect with different drugs to pregnancy in?duced hypertension syndrome. Methods 144 cases of PIH patients in our hospital were randomly divided into two groups:the control group were treated by magnesium sulphuricum. The study group was treated by magnesium sulphuric?um and infused nitroglycerin with micro pump. The clinical curative effect, Changes of blood pressure, 24 h urine protein quantity, and the outcome of pregnancy of two groups were observed and compared. Results The total efficiency of study group was significantly higher than thatofcontrol group (90.28%vs 73.61) (P<0.05);Systolic blood pressure, dia?stolic blood pressure, 24 h urine protein of the study group were decreased significantly than that of control group (P<0.05) after treatment;placental abruption, cesarean section birth, postpartum hemorrhage, fetal distress and neonatal as?phyxia in study group were premature delivery, the probability ofthe outcome of pregnancy was significantly lower than the control group (P<0.05). Conclusion The clinical application of nitroglycerin micro pump assisted with magnesium sulphuricum in the treatment of PIH can reduce blood pressure significantly and improve the prognosis of pregnancy.