CAJ | 학술논문

目的：建立中药制剂中桉油精、薄荷脑的含量测定方法。方法采用气相色谱法，ZB-WAX弹性石英毛细管柱（30 m ×0.25 mm，0.25μm）；环己酮为内标。结果桉油精和薄荷脑的线性范围分别为0.146～2.555 mg·mL-1（R2=0.9999）、0.198～3.465 mg·mL-1（R2=0.9998）；平均加样回收率分别为99.8%、99.5%（n=9），桉油精与薄荷脑的最低定量限浓度分别为6.27、9.90μg·mL-1；最低检测限浓度分别为1.044、1.65μg·mL-1。结论方法简便、快速、准确、分离度好、其他成分无干扰，适用于复方制剂中多成分的质量控制。
목적：건립중약제제중안유정、박하뇌적함량측정방법。방법채용기상색보법，ZB-WAX탄성석영모세관주（30 m ×0.25 mm，0.25μm）；배기동위내표。결과안유정화박하뇌적선성범위분별위0.146～2.555 mg·mL-1（R2=0.9999）、0.198～3.465 mg·mL-1（R2=0.9998）；평균가양회수솔분별위99.8%、99.5%（n=9），안유정여박하뇌적최저정량한농도분별위6.27、9.90μg·mL-1；최저검측한농도분별위1.044、1.65μg·mL-1。결론방법간편、쾌속、준학、분리도호、기타성분무간우，괄용우복방제제중다성분적질량공제。
OBjective ToestablishamethodforthedererminationofeucalyptolandmentholinDhinesemedicine preparations. Methods Gas chromatography,the ZB-WAX elastic quartz capillary column(30 m × 0. 25 mm,0. 25 μm);Dyclohexanone as internal standard. Results The linear range of eucalyptol and menthol was 0. 146~2. 555 mg·mL-1 (R2 =0. 999 9),0. 198~3. 465 mg·mL-1(R2 =0. 999 8);The average sample recovery rates were 99. 8%,99. 5%,re-spectively(n=9),the minimum quantitative limit concentrations of eucalyptol and of menthol were 6. 27,9. 90μg·mL-1;The minimum detection limit concentrations were 1. 044,1. 65 μg·mL-1 . Conclusion The method was simple,rapid,ac-curate,good separating degree,no interfere with other ingredients and was applicable to many ingredients in the compound preparation of quality control.