CAJ | 학술논문

目的：探讨β－受体阻滞剂干预更年期妇女心电图变化的临床价值。方法选取无器质性疾病但有心电图改变的更年期妇女62例，经患者知情同意按照数字表法随机分为治疗组31例，予以β－受体阻滞剂治疗3周；另31例为对照组，不给予任何治疗。观察治疗前后2组间及治疗组心电图指标（心率、心律、ST－T）的改变。结果（1）经β－受体阻滞剂治疗3周后，2组平均心率、心律、ST－T改变（除ST上斜外）比较差异均有统计学意义（P＜0．05）。（2）治疗组治疗前后比较，成对房早、ST上斜和T波倒置虽有改变，但差异无统计学意义（P＞0．05）；其余指标均有明显改变，差异有统计学意义（P＜0．05）。结论β－受体阻滞剂应用于心电图改变的更年期妇女有一定的临床价值。
목적：탐토β－수체조체제간예경년기부녀심전도변화적림상개치。방법선취무기질성질병단유심전도개변적경년기부녀62례，경환자지정동의안조수자표법수궤분위치료조31례，여이β－수체조체제치료3주；령31례위대조조，불급여임하치료。관찰치료전후2조간급치료조심전도지표（심솔、심률、ST－T）적개변。결과（1）경β－수체조체제치료3주후，2조평균심솔、심률、ST－T개변（제ST상사외）비교차이균유통계학의의（P＜0．05）。（2）치료조치료전후비교，성대방조、ST상사화T파도치수유개변，단차이무통계학의의（P＞0．05）；기여지표균유명현개변，차이유통계학의의（P＜0．05）。결론β－수체조체제응용우심전도개변적경년기부녀유일정적림상개치。
Objective To investigate the clinical significance of beta-receptor blocker intervention on ECG changes in climac-teric women.Methods Sixty-two subjects of climacteric women without organic diseases but with ECG changes were chosen and ran-domly divided into 2 groups:the control group(n=32)and the treatment group(n=30).The subjects of the control group were not giv-en any treatment, while the subjects of the treatment group were given treatment of beta-receptor blocker intervention for 3 weeks.ECG changes ( heart rate, rhythm and ST-T changes) were detected both before and after treatment, and then, comparisons were made be-tween the groups and within the groups.Results ( 1 ) After 3 weeks of beta-receptor blocker intervention, significant ECG changes could be noted in heart rate, rhythm and ST-T changes ( except ST cable) in the subjects of the treatment group, with statistical signifi-cance, when comparisons were made between the 2 groups (P<0.05).(2)In treatment group, though changes were seen in the paired atrial premature beat ( APB) , ST cable and T wave inversion, there no statistic significance, when comparisons were made between pre and post treatment (P>0.05).There were significant changes in the remaining parameters, with statistical significance (P<0.05). Conclusion Beta-receptor blocker had its clinical value, when it was used in climacteric women with ECG changes.